软斑病是一种罕见的、可治愈的、有一定自限性的慢性肉芽肿炎症性疾病,确诊依赖于病理组织学的检查,临床一般使用强效抗生素或抗生素与手术切除联合治疗。目前国内对于该病的文献报道较少,其多发生于泌尿生殖系统,发生于阴道残端者比较少见。本文报告1例老年女性阴道残端软斑病例的诊断及保守治疗情况,以提高对本病的认识。
Malakoplakia is a rare, curable, and self-limited chronic granulomatous inflammatory disease. The diagnosis of malakoplakia depends on histopathological examination. Malakoplakia can be treated with strong antibiotics or antibiocits combined with surgery. Case reports of malakoplakia are rarely seen in China at present. It occurs more often in the genitourinary system, and hardly in the vaginal stump. Here we reported the diagnosis and conservative treatment of an elderly female case of vaginal stump malakoplakia, aiming to raise the understanding of the disease.
[1] 刘丽燕,刘永建,邓永敏,等.软斑病4例临床病理分析[J]. 诊断病理学杂志,2013,20(10):600-603.
[2] 万晓芳,魏文斐,王薇等.子宫内膜软斑病1例报告[J]. 中国医学创新,2014,11(15):155-156.
[3] 甄美凤,黄雪萍,陶莉莉.子宫内膜软斑病1例[J]. 中国计划生育和妇产科,2020,12(1):93-96.
[4] 顾伟勇,张丽虹,曲玉清.女性生殖道软斑病3例临床病理分析[J]. 临床与实验病理学杂志,2018,34(5):548-550.
[5] 李萌萌,金英子,南云泽.阴道断端软斑病1例报告[J]. 中国实用妇科与产科杂志,2018,34(2):239-240.
[6] Chadha S, Vuzevski VD, Kate FJW.Malakoplakia of the endometrium: a rare cause of postmenopausal bleeding[J]. Eur J Obstet Gynecol Reprod Biol, 1985, 20(3): 181-189.
[7] Kiely NP, Anderson L, Arora H, et al.A novel cause of postmenopausal bleeding in an immunosuppressed patient[J]. BMJ Case Rep, 2018, 2018: bcr2018225642.
[8] Yousef GM, Naghibi B, Hamodat MM.Malakoplakia outside the urinary tract[J]. Arch Pathol Lab Med, 2007, 131(2): 297-300.
[9] Dong H, Dawes S, Philip J, et al.Malakoplakia of the urogenital tract[J]. Urol Case Rep, 2015, 3(1): 6-8.
[10] Cho JS, Kim HI, Lee JY, et al.Pelvic malakoplakia presenting as endometrial cancer: a case report[J]. Obstet Gynecol Sci, 2020, 63(4): 538-542.
[11] Kogulan PK, Smith M, Seidman J, et al.Malakoplakia involving the abdominal wall, urinary bladder, vagina, and vulva: case report and discussion of malakoplakia-associated bacteria[J]. Int J Gynecol Pathol, 2001, 20(4): 403-406.
