目的 分析钬激光前列腺剜除术治疗大体积良性前列腺增生（BPH）的有效性及安全性。方法 回顾性分析2021年3月—2024年3月收治的73例大体积BPH患者临床资料,按照治疗方法的不同分为电切组和钬激光组。将接受经尿道前列腺双极等离子电切术的36例患者设为电切组,接受经尿道钬激光前列腺剜除术的37例患者设为钬激光组。对比两组患者的手术相关指标、前列腺改善情况以及术后并发症发生情况。结果 钬激光组的手术相关时间指标均短于电切组,术中出血量较少（P<0.05）。治疗后,钬激光组患者的最大尿流率（Q_max）大于电切组,残余尿量（PVR）和国际前列腺症状评分（IPSS）小于电切组（P<0.05）。术后,钬激光组的并发症发生率为8.11%（3/37）,与电切组的13.89%（5/36）相比,差异无统计学意义（P>0.05）。结论 采用钬激光前列腺剜除术治疗大体积BPH可缩短手术时间、减少术中出血,有利于提升预后效果,并降低术后并发症发生风险,建议推广应用。

Objective To evaluate the effectiveness and safety of holmium laser prostatectomy for the treatment of large volume benign prostatic hyperplasia （BPH）. Methods A retrospective analysis was conducted on the clinical data of 73 patients with large volume BPH admitted from March 2021 to March 2024. According to different treatment methods, they were divided into an electric resection group and a holmium laser group. Among them,36 patients who underwent transurethral bipolar plasma resection of the prostate were assigned to the electric resection group, and 37 patients who underwent transurethral holmium laser prostatectomy were assigned to the holmium laser group. Surgical related indicators, prostate improvement, and postoperative complications were compared between the two groups of patients. Results The surgery related time indicators in the holmium laser group were shorter than those in the electric resection group, and the intraoperative bleeding was less （P<0.05）. After treatment, the maxmium urine flow rate （Q_max） of patients in the holmium laser group was higher than that in the electric resection group, while the postvoid residual （PVR） and international prostate symptom score （IPSS） were lower （P<0.05）. After designed surgery, the incidence of complications in the holmium laser group was 8.11% （3/37）, which was not significantly different from the 13.89% （5/36） in the electric resection group （P>0.05）. Conclusion The use of holmium laser prostatectomy for the treatment of large volume BPH can shorten surgical time, reduce intraoperative bleeding volume, improve prognosis, and reduce the risk of postoperative complications. It is recommended to application.