The HCC (hepatocellular carcinoma,HCC) has high incidence,treatment of intractable,and the prognosis is poor,lt needs combined therapy.The radical treatment including surgical resection,liver transplantation,TACE,radiofrequency,ablation,immunotherapy and so on.In recent years with sorafenib as a representative of the molecular targeted drugs shows significant curative effect in treating HCC.This review aims to collecting the latest related researches about sorafenib in HCC in recent years,and carries on the classified analysis,in order to have a comprehensive understanding to guide its clinical application.
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