Due to the complex structure of mitral valve and its surrounding tissues, technique of minimally invasive treatment of mitral valve diseases was started late. At present, only Mitraclip technique is selectively used in some developed countries to treat mitral regurgitation. However, new technologies have leaped forward. Nowadays, various prototypes of minimally invasive treatment of mitral valve diseases are in different stages of experimental or preclinical study. In this review, these technologies of minimally invasive treatment are summarized.