[摘要]目的：观察内镜下黏膜切除术治疗大肠广基息肉的临床效果。方法：选择2014年1月-2015年2月来我院治疗大肠广基息肉的患者86例，随机将其分成对照组和治疗组两组，每组43例。对照组患者采用内镜下氩气刀凝固的方式进行治疗，治疗组患者采用内镜下黏膜切除术治疗，观察两组患者治疗效果。结果：治疗组患者在疗效、手术安全性、复发率方面与对照组患者存在明显差异，差异有统计学意义(P＜0.05)。结论：对大肠广基息肉患者采用内镜下黏膜切除术治疗，能有效提高疗效、满意度，降低复发率，手术安全性高，可推广应用。

Abstract Objective: To investigate the clinical effect of endoscopic mucosal resection in treating large intestine sessile colorectal polyp. Methods: 86 cases with large intestine sessile colorectal polyp in our hospital from January 2014 to February 2015 were selected and divided into control group and observation group, 43 cases in each group. The control group was given endoscopic argon plasma coagulation and observation group was given endoscopic mucosal resection. Observed the clinical effect of the two groups. Results: Effect, operation safety and recurrence rate of observation group had obvious difference, the difference was statistically significant (P＜0.05). Conclusion: Endoscopic mucosal resection in treating large intestine sessile can improve curative effect and satisfaction rate, lower the recurrence rate. It has higher operation safety and is worthy of application.