探讨肝动脉栓塞化疗联合射频消融序贯治疗与常规手术单纯切除小肝癌的疗效差异。方法选取2010年1月～2012年2月来我院住院治疗的50例小肝癌患者作为观察对象，并随机分为两组，一组采用常规手术切除小肝癌，另一组采用肝动脉栓塞化疗联合射频消融序贯治疗，比较两组患者不同方式治疗后1年、2年、3年的生存率、肿瘤复发率，及其相关并发症情况。结果两组患者经过不同方式治疗后，观察组治疗后并发症显著少于对照组（P＜0.05），治疗后1、2、3年的累积复发率，观察组为：12.0%、16.0%、32.0%，对照组为：12.0%、16.0%、32.0%（P＞0.05）；治疗后1、2、3年的生存率，对照组为：92.0%、76.0%、56.0%，观察组为：92.0%、80.0%、60.0%（P＞0.05）。结论采用肝动脉栓塞化疗联合射频消融序贯治疗小肝癌患者，疗效确切，远期预后与手术疗效无明显差异，并发症较少，可作为小肝癌患者首选之一。

SummaryObjective To explore the hepatic artery chemoembolization combined with radiofrequency ablation difference in efficacy of sequential therapy and conventional surgical resection alone small hepatocellular carcinoma.Methods 50 cases in January 2011 - February 2014 to our hospital patients with small hepatocellular carcinoma as the observed object, and randomly divided into two groups, one group received conventional surgical resection of small hepatocellular carcinoma, and the other group received TACE radiofrequency ablation, different ways were compared after 1 year, 2 years, 3-year survival rate of tumor recurrence, and its associated complications.Results Two groups of patients after treatment in different ways, the observation group after treatment of complications was significantly less than the control group (P <0.05), the cumulative relapse rate after treatment 1, 2, 3 years, the observation group: 12.0%, 16.0%, 32.0 % in the control group: 12.0%, 16.0%, 32.0% (P> 0.05); after treatment 1, 2, 3-year survival rate of the control group: 92.0%, 76.0%, 56.0% in the observation group was: 92.0 %, 80.0%, 60.0% (P> 0.05).Conclusion TACE combined with RFA sequential treatment of small hepatocellular carcinoma patients, efficacy, no significant difference in long-term prognosis with surgery, fewer complications, can be used as one of small hepatocellular carcinoma patients preferred.