目的 探讨七氟醚复合瑞芬太尼麻醉对腹腔镜子宫切除术患者的治疗效果。方法 回顾性分析2016年2月—2018年3月行腹腔镜子宫切除术治疗的86例患者的临床资料,依据麻醉方案的不同,分为观察组(七氟醚复合瑞芬太尼麻醉,43例)与对照组(丙泊酚复合瑞芬太尼麻醉,43例),比较两组应激反应及认知功能。结果 气腹30 min与手术结束时,观察组肾上腺素、皮质醇水平及心率值均低于对照组,术后1 d,MMSE评分高于对照组,差异有统计学意义(P＜0.05)。结论 腹腔镜子宫切除术患者通过氟醚复合瑞芬太尼麻醉,可有效缓解手术应激反应,且对认知功能影响相对较小。

Objective To investigate the effect of sevoflurane combined with remifentanil anesthesia in patients with laparoscopic hysterectomy.Methods The clinical data of 86 patients with laparoscopic hysterectomy from February 2016 to March 2018 were retrospectively analyzed.The cases were divided into observation group (sevoflurane combined with remifentanil anesthesia, 43 cases) and control group (propofol combined with remifentanil anesthesia, 43 cases) according to anesthesia regimens.The stress response and cognitive function were compared between the two groups.Results After pneumoperitoneum for 30 min and at the end of surgery, the epinephrine, cortisol, and heartrate of the observation group were lower than those of the control group, but the postoperative 1d MMSE score of the observation group was higher than that of the control group (P<0.05).Conclusion Sevoflurane combined with remifentanil anesthesia for patients with laparoscopic hysterectomy can effectively relieve surgical stress response, and have less effect on cognitive function.