目的 探讨糖尿病下肢血管病变的超声诊断及临床价值。方法 选择2016年1月—2016年12月收治的50例糖尿病下肢血管病变患者为观察组,另选择同期非糖尿病患者50例作为对照组,两组观察对象均行下肢血管彩色多普勒超声,并对两组患者的超声影像特点进行比较分析。结果 50例观察组患者中,发生血管损伤患者为47例(94.0%);其中多普勒超声检查结果显示斑块41例,阳性率87.23%(41/47),管腔狭窄14例,阳性率29.79%(14/47),管腔闭塞11例,阳性率23.40%(11/47);对照组50例观察对象中,发生血管损伤患者为22例(44.0%);其中多普勒超声检查结果显示斑块13例,阳性率59.09%(13/22),管腔狭窄4例,阳性率18.18%(4/22),无血管闭塞,两组下肢血管损伤阳性率、血管斑块、管腔狭窄、管腔闭塞比较,差异均有统计学意义(P<0.05);从下肢血管多普勒超声影像学观察,观察组患者下肢血管与对照组观察对象比较,管腔明显狭窄,血流减少,频谱宽度增宽。结论 超声用于糖尿病下肢血管病变检查,下肢血管损伤检出率高,且操作简单、无创,为该疾病的早期临床诊断及治疗提供重要影像学依据。
Objective To evaluate the ultrasound diagnosis of diabetic lower limb vascular lesions and its clinical value.Methods From January to December 2016,patients with diabetic lower extremity vascular disease (n=50) admitted to Xuyi County People’s Hospital of Huai’an City were enrolled as observation group,and non-diabetic patients (n=50) were enrolled as control group.Both groups received lower extremity vascular color Doppler ultrasound,and the ultrasonographic features of the two groups were compared and analyzed.Results Of the 50 observation cases,47 cases (94%) had vascular injury.Specifically,the Doppler ultrasound examination results showed plaque in 41 cases (41/47,87.23%),stenosis in 14 cases (14/47,29.79%),and luminal occlusion in 11 cases (11/47,23.40%).Of the 50 control cases,22 cases (44%) had vascular injury.Specifically,the Doppler ultrasound examination results showed plaque in 13 cases (13/22,59.09%),stenosis in 4 cases (4/22,18.18%),and no vascular occlusion.The positive rates of lower extremity vascular injury,vascular plaque,stenosis,and luminal occlusion were significantly different betweent the two groups (P<0.05).According to the lower extremity vascular Doppler ultrasound imaging,compared with the control group,the observation group showed luminal stenosis,blood flow reduction,and spectrum width broadening.Conclusion Ultrasonography shows a high detection rate of lower extremity vascular injury.The simple and non-invasive precedure provides important imaging evidence for early diagnosis and treatment for the disease.
[1] 徐瑜.中国成人糖尿病流行与控制现状——2010年中国慢病监测暨糖尿病专题调查报告解读[J].中华内分泌代谢杂志,2014,3(30):184-186.
[2] 高林英,任文霞,冯永亮.2型糖尿病下肢血管病变的临床流行病学分析[J].中华疾病控制杂志,2014,18(4):308-311.
[3] 中华医学会糖尿病学分会.中国2型糖尿病防治指南(2013年版)[J].中华糖尿病杂志,2014,6(7):447-498.
[ 4 ] Tabit CE,Chung WB, Hamburg NM,et al. Endothelial dys-function in diabetes mellitus:molecular mechanisms and clinical implications[J].Rev Endocr Metab Disord,2010,11(1):61-74.
[5] 童奥,马小艳,朱慧娟.等.567例糖尿病足患者的综合护理实践[J].中华损伤与修复杂志(电子版),2013,8(3):304-306.
[6] 王莉,杨彩哲,关小宏,等.糖尿病下肢血管病变横断面研究及相关因素分析[J].中华老年医学杂志,2014,33(7):760-763.
[7] 陆明晰,叶有新,蒋欣欣,等.超声介入治疗血液透析移植血管动静脉内瘘狭窄的应用研究[J].中华超声影像学杂志,2012,21(10):913-914.
[8] 刘亚,刘娅妮,邓又斌.超声造影在动脉粥样硬化病变中的应用[J].中华超声影像学杂志,2014,23(1):76-78.