隆突性皮肤纤维肉瘤是一种低度恶性的纤维组织细胞肿瘤,发病率低,中年男性多见,确诊需组织病理检查,治疗首选手术切除,但术后易复发。文章报告2例女性患者,行扩大切除术后均无复发。
Dermatofibrosarcoma protuberans is a low-grade malignant fibrous tissue neoplasm with a low incidence,and primarily affects middle-aged men.Histopathological examinations are required to confirm diagnosis of dermatofibrosarcoma protuberans.The first choice for treatment is surgical resection,but the disease is subject to relapse.This article reported two female dermatofibrosarcoma protuberans patients with no recurrence after extended surgical resection.
[1] Castle KO,Guadagnolo BA,Tsai CJ,et al.Dermatofibrosarcoma protuberans:long-term outcomes of 53 patients treated with conservative surgery and radiation therapy[J].IJROBP,2013,86(3):585-590.
[2] 温斯健,胡彬,杨励,等.隆突性皮肤纤维肉瘤50例临床病理分析[J].中华皮肤科杂志,2015,(12):840-843.
[3] 张锦,周晓军,马捷.纤维肉瘤样隆突性皮肤纤维肉瘤诊治研究进展[J].临床皮肤科杂志,2014,43(4):257-260.
[4] 先疆燕,王忠,王荣丽,等.手术部位感染危险因素的meta分析[J].外科研究与新技术,2017,6(1):39-43.
[5] Suman S,Sharma P,Jain TK,et al.Recurrent dermatofibrosarcoma protuberans with pulmonary metastases presenting twelve years after initial diagnosis:18F-FDG PET/CT imaging findings[J].CNM,2014,39(1):77-78.
[6] Fields RC,Hameed M,Qin L,et al.Dermatofibrosarcoma protuberans (DFSP):predictors of recurrence and the use of systemic therapy[J].ASO,2011,18(2):328-336.
