目的 观察高压氧联合电针“四关”穴对脑卒中早期认知障碍的影响。方法 将90例脑卒中轻度认知障碍的患者随机分为针刺“四关”组,高压氧治疗组,高压氧联合针刺“四关”组,观察治疗前后的疗效。结果 针刺“四关”穴或高压氧治疗组2个疗程后均可提高脑卒中患者简明精神状态检查量表(MMSE)评分(P<0.05),而高压氧联合针刺“四关”穴治疗1个疗程后可提高脑卒中患者的MMSE评分(P<0.05),且治疗2个疗程后与高压氧治疗组、针刺“四关”组差异有统计学意义(P<0.05)。结论 高压氧联合针刺“四关”穴能明显改善脑卒中患者的认知障碍,且较单用针刺与高压氧治疗为优。
Objective To observe the effects of hyperbaric oxygen combined with electroacupuncture at Siguan acupoint on early cognitive impairment in stroke patients.Methods Ninety stroke patients with mild cognitive impairment were randomly divided into Siguan acupuncture group, hyperbaric oxygen group,and hyperbaric oxygen combined with Siguan acupuncture group. The therapeutic effects were observed before and after treatment.Results After two courses of treatment, the Siguan acupuncture group and the hyperbaric oxygen group showed improved MMSE score (P<0.05). After one course of treatment, the hyperbaric oxygen combined with Siguan acupuncture group showed improved MMSE score (P<0.05). After two courses of treatment, there was a significant difference in the MMSE score among the three groups (P<0.05).Conclusion Hyperbaric oxygen combined with acupuncture at Siguan acupoint can significantly improve cognitive impairment in stroke patients and is superior to acupuncture or hyperbaric oxygen therapy alone.
[1] 中华神经科学会,中华神经外科学会.各类脑血管疾病诊断要点[J].临床和实验医学杂志,2013,12(7):559-560.
[2] 苗黎黎,孙善斌.中风后认知功能障碍的中医治疗及研究[J].中医药临床杂志,2017,29(5):626-628.
[3] 叶海敏,张鹏,林旭明,等.针刺“四关”穴治疗脑卒中后抑郁的临床研究[J].中医药导报,2016,22(7):59-62.
[4] 刘畅,张虹.针刺四关穴在心身疾病中的运用与研究[J].四川中医,2017,35(3):217-219.
[5] Liu PR, Zhou Y, Zhang Y, et al.Electroacupuncture alleviates surgery-induced cognitive dysfunction by increasing α7-nAChR expression and inhibiting inflammatory pathway in aged rats[J].Neurosci Lett,2017,659(17):1-6.
[6] Shandley S, Wolf EG, Schubert-Kappan CM, et al.Increased circulating stem cells and better cognitive performance in traumatic brain injury subjects following hyperbaric oxygen therapy[J].Undersea Hyperb Med,2017,44(3):257-269.