目的 观察腹腔镜结直肠癌根治术治疗结直肠癌的近期疗效。方法 选取2016年1月—2019年1月施行腹腔镜结直肠癌根治术治疗的36例结直肠癌作为腹腔镜组,同期行开腹结直肠癌根治术治疗的22例结直肠癌为开腹对照组,对比分析两组的近期治疗效果。结果 腹腔镜组手术时间、术中出血量、术后首次排气时间及开始进食时间显著优于开腹组（P<0.05）。两组淋巴结清扫数目、肿瘤远端长度无差异。开腹组术后血清IL-6、IL-8水平显著高于腹腔镜组（P<0.05）。结论 腹腔镜结直肠癌根治术治疗结直肠癌与开腹手术效果相当,但手术创伤较小,更安全。

Objective To observe the short-term effect of laparoscopic radical operation for colorectal cancer. Methods Thirty-six patients with colorectal cancer undergoing laparoscopic radical surgery from January 2016 to January 2019 were selected as laparoscopic group, and 22 patients with colorectal cancer undergoing open radical surgery at the same time were selected as laparotomy control group. The short-term therapeutic effects between the two groups were compared and analyzed. Results Longer operation time, less intraoperative blood loss, shorter postoperative first exhaust time, and shorter feeding time in the laparoscopic group were observed than those in the laparotomy group (P<0.05). No differences in the number of lymph node dissection and the length of distal end of tumor between the two groups were observed. The levels of serum IL-6 and IL-8 in the laparotomy group was significantly higher than those in the laparoscopic group. Conclusion Laparoscopic radical operation is as effective as laparotomy, but less invasive and safer for colorectal cancer.