目的 观察腹腔镜胃癌根治术中予以腹腔灌注治疗进展期胃癌的疗效。方法 选取82例接受腹腔镜胃癌根治术治疗的患者,按随机数字表法分观察组和对照组,每组各41例,对照组仅行腹腔镜胃癌根治术,观察组行腹腔镜胃癌根治术和术中腹腔灌注,比较两组疗效。结果 观察组术后置管引流时间、住院时间短于对照组（P<0.05）,术后12个月癌症复发率低于对照组（P<0.05）;但两组手术时间、术中出血量、术后肛门排气时间,以及术后并发症不良反应发生率、术后6个月癌症复发率无差异。结论 腹腔镜胃癌根治术中予腹腔灌注治疗进展期胃癌安全有效,可有效缩短住院时间,延缓癌症复发进程,值得推广。

Objective To observe the effect of intraperitoneal perfusion during laparoscopic radical gastrectomy on advanced gastric cancer. Methods Eight two patients with advanced gastric cancer undergoing laparoscopic radical gastrectomy were randomly divided into a control group (n=41) and an observation group (n=41) by random number table method. The control group received laparoscopic radical gastrectomy only, and the observation group received laparoscopic radical gastrectomy and intraoperative intraperitoneal perfusion. The therapeutic effects were compared between the two groups. Results The postoperative drainage time, hospitalization time, and disease recurrence rate after 12 months of the observation group were shorter and lower than those of the control group (P<0.05); but no significant differences in operation time, intraoperative blood loss volume, postoperative exsufflation time, postoperative complication and side effect rates, and disease recurrence after 6 months were observed between the two groups. Conclusion Intraperitoneal perfusion during laparoscopic radical gastrectomy for advanced gastric cancer is safe and effective, can shorten hospitalization time and delay recurrence, and is worth promoting.