目的 观察近视患者中央孔型有晶体眼人工晶体ICL V4C 植入术后对眼压的影响。方法 选取2016年1月—2017年1月收治的近视24例（48眼）的临床资料,所有患者均行ICL V4C植入术,均为同一手术医师。年龄21~45岁,平均（32.8±6.5）岁,等效球镜-4D~-18D,平均（8.25±4.5）D,散光-0.5D~-4D,平均（1.25±0.75）D。眼压在10~21 mmHg,平均（15.9±2.82） mmHg。术后拱高150~750 μm,术后随访3年,观察有晶体眼人工晶体ICL V4C植入术对眼压的影响。结果 患者术后1周、1个月、3个月、6个月、1年、2年、3年眼压值均在10~21 mmHg,均未超过正常安全范围。两只眼睛之间的差异均小于5 mmHg。在术前1周及术后1周、1个月、3个月、6个月、1年、2年、3年的差异具有统计学意义（P<0.05）。结论 近视患者行有晶体眼后房型人工晶体ICL V4C植入手术后眼压均在正常安全范围内,术后3年观察眼内植入人工晶体后眼压与术前相比没有明显变化。

Objective To observe the effect of implantation of implantable collamer lens with a central hole （ICL V4C） on intraocular pressure in patients with myopia. Methods Clinical data of 24 cases （48 eyes） from January 2016 to January 2017 were retrieved. All patients received ICL V4C implantation by the same operator. The patients were aged 21 to 45 years, average （32.8±6.5） years. The equivalent ball mirror was -4D~-18D, average （8.25±4.5） D. The astigmatism was between -0.5 D and -4 D, average （1.25±0.75） D. The intraocular pressure ranged between 10-21 mmHg with an average of （15.9±2.82） mmHg. The postoperative arch height was 150-750 μm. The patients were followed up for three years to observe the effect of ICL V4C implantation on intraocular pressure. Results The intraocular pressure values of patients at 1 week, 1 month, 3 months, 6 months, 1 year, 2 years, and 3 years after the operation were all within the range of 10-21 mmHg, which did not exceed threshold. The difference between the two eyes were all less than 5 mmHg and significantly lower than that of the control group （P<0.05）. Conclusion The intraocular pressures of myopic patients are all within a normal and safe range after ICL V4C implementation, and are not obviously changed three years after the surgery compared with before.