目的 探讨输尿管镜下气压弹道碎石术（URSL）治疗输尿管中下段结石并发感染患者的临床效果。方法 选择2017年1月—2020年7月间收治的输尿管中下段结石患者,选取其中60例合并感染症状的患者为研究对象,参照随机分层法将患者分为对照组（n=30）和研究组（n=30）,给予对照组体外冲击波碎石术（ESWL）治疗,给予研究组URSL治疗,比较两组治疗效果。结果 研究组一次性结石清除成功率（90%）明显高于对照组（76.67%）,并发症发生率（6.67%）明显低于对照组（26.67%）,差异显著（P<0.05）。对照组和研究组治疗前降钙素原、尿白细胞计数（LEU）、超敏C反应蛋白（hs-CRP）、肌酐和血常规白细胞计数的水平间无明显差异（P>0.05）,治疗后研究组上述5项指标的水平明显低于对照组,差异显著（P<0.05）。结论 对输尿管中下段结石患者使用URSL治疗,其效果远胜于ESWL治疗,临床应用价值显著。

Objective To investigate the clinical effect of ureteroscopic lithotripsy using Swiss Lithoclast （URSL） on middle and lower ureteral calculi complicated with infection. Methods Sixty middle and lower ureteral calculi patients with infection treated from January 2017 to July 2020 were selected and divided into a control group （n=30） and a study group （n=30） by random stratification method. The control group was treated with extracorporeal shock wave lithotripsy （ESWL）; the study group was treated with URSL. Surgical effects were probed. Results The one-time removal rate in the study group （90%） was higher than that in the control group （76.67%）. The complication rate in the study group （6.67%） was lower than that in the control group （26.67%, P<0.05）. Before surgery, the levels of procalcitonin, leukocyte （LEU）, hypersensitive C-reactive protein （hs-CRP）, creatinine, and white blood cell count between the two groups were not significantly different （P>0.05）： After surgery, the five indicators in the study group were significantly lower than those in the control group （P<0.05）. Conclusion URSL has better effects than ESWL for middle and lower ureteral calculi patients.