目的 探讨白内障手术患者晶状体后囊膜破裂（PCR）发生的影响因素。方法 回顾性收集2018年5月—2020年5月接受手术治疗且完成随访的白内障患者临床资料,并从中筛选符合条件的73例患者作为研究对象,根据术中晶状体PCR发生情况,分为发生组（n=16）与未发生（n=57）。仔细阅读所有患者临床资料,并将可能的影响因素纳入,经单因素与多因素分析找出白内障手术患者晶状体PCR发生的影响因素。结果 经logistic回归分析检验结果显示,男性、晶状体核分型≥Ⅲ级、合并玻璃体积血均是白内障手术患者晶状体PCR发生的影响因素OR（95%CI）分别为18.121（4.392~74.767）、18.700（4.829~72.417）、37.333（7.215~193.187）,均P<0.05。结论 白内障手术患者晶状体PCR发生受多种因素影响,其中男性、晶状体核分型≥Ⅲ级、合并玻璃体积血为重要的危险因素,临床需重点关注,并积极实施预防与治疗措施,以期降低白内障手术患者晶状体PCR的发生率。

Objective To investigate the influencing factors of lens posterior capsule rupture （PCR） in patients with cataract surgery. Methods The clinical data of 73 patients with cataract who underwent surgery and completed follow-up from May 2018 to May 2020 were retrospectively analyzed. According to the occurrence of intraoperative lens PCR, they were divided into an occurrence group （n=16） and a non-occurrence group （n=57）. Possible influencing factors of lens PCR in patients with cataract surgery were included after careful review of their clinical data, and identified through univariate and multiple logistic regression analyses. Results The results of multiple logistic regression analysis showed that male, lens nucleus hardness ≥ grade Ⅲ, and combination with vitreous hemorrhage were the influencing factors for the occurrence of lens PCR in patients with cataract surgery, and coresponding OR （95%CI） were 18.121 （4.392-74.767）, 18.700 （4.829-72.417）, and 37.333 （7.215-193.187）, respectively, all P<0.05. Conclusion The occurrence of lens PCR in patients with cataract surgery is associated with multiple factors such as male, lens nucleus hardness ≥ grade Ⅲ, and combination with vitreous hemorrhage. Close attention in clinical care and active prevention and control measures are required to reduce the incidence of lens PCR in patients with cataract surgery.