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阿芬太尼和舒芬太尼复合丙泊酚麻醉在无痛气管镜检查中的应用比较

  • 李菁
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  • 上海中医药大学附属龙华医院麻醉科,上海 200032
李 菁(1988—),女,大学本科,住院医师,从事临床麻醉科工作;电子信箱:49732880@qq.com

收稿日期: 2022-06-16

  网络出版日期: 2023-03-20

Comparison of alfentanil and sufentanil combined with propofol anesthesia in painless bronchoscopy

  • LI Jing
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  • Department of Anesthesiology, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China

Received date: 2022-06-16

  Online published: 2023-03-20

摘要

目的 观察无痛气管镜检查中应用阿芬太尼或舒芬太尼复合丙泊酚的麻醉效果比较。方法 选取2021年3月—2021年7月期间行无痛气管镜检查的患者80例。按照随机数字表法分为对照组与观察组各40例。分别采用舒芬太尼(0.2 μg/kg)和阿芬太尼(20 μg/kg)全麻诱导,记录两组患者麻醉诱导前,诱导后3 min以及检查结束时平均动脉血压,苏醒时间,定向力恢复时间,呼吸抑制,呛咳等不良反应。结果 与对照组比较,观察组麻醉诱导后3 min及检查结束时平均血压下降幅度明显低于对照组,差异具有统计学意义(P<0.05)。观察组的苏醒以及定向力恢复时间都显著小于对照组(P<0.05)。结论 无痛气管镜检查采用阿芬太尼复合丙泊酚麻醉,苏醒时间快,血流动力学更平稳,定向力恢复时间短。

本文引用格式

李菁 . 阿芬太尼和舒芬太尼复合丙泊酚麻醉在无痛气管镜检查中的应用比较[J]. 外科研究与新技术(中英文), 2022 , 11(4) : 257 -259 . DOI: 10.3969/j.issn.2095-378X.2022.04.007

Abstract

Objective To observe and compare the anesthesia effects of alfentanil and sufentanil combined with propofol in painless bronchoscopy. Methods A total of 80 patients who underwent painless bronchoscopy from March 2021 to July 2021 were selected. According to random number table method, they were divided into a control group and an observation group, 40 cases in each group. Sufentanil was used in the control group (0.2 μg/kg), and at alfentanil in the control group (20 μg/kg). Mean blood pressure (before induction of anesthesia, 3 min after induction, and the end of the examination), wake-up time, orientation recovery time, respiratory depression, coughing and other adverse reactions were recorded in the two groups. Results The mean blood pressure levels of the observation group 3 min after induction and after examination in the observation group declined less than those in the control group (P<0.05). The wake-up time and orientation recovery time of the observation group were shorter than those of the control group (P<0.05). Conclusion Painless bronchoscopy using alfentanil combined with propofol anesthesia results in quick recovery time, stable hemodynamics, and short recovery time for orientation.

参考文献

[1] 国家消化内镜质控中心,国家麻醉质控中心. 中国消化内镜诊疗镇静/ 麻醉操作技术规范[J]. 临床麻醉学杂志,2019, 35(1):81-84.
[2] Becker HD.Bronchoscopy: the past,the present,and the future[J].Clin Chest Med, 2010, 31(1):1.
[3] 王金伙,郭建荣.阿芬太尼的临床药理特性及其麻醉应用进展. 中国临床药理学与治疗学,2021,26(7): 824-829.
[4] 周梅,梅同华,陈玉培,等.镇静无痛苦纤支镜检查中芬太尼联合异丙酚的最佳用量研究[J].国际呼吸杂志,2008, 28(24):1496.
[5] 付露阳,李洪超,陈平钰,等. 舒芬太尼联合地佐辛与单用舒芬太尼比较用于术后镇痛有效性和安全性的 Meta分析[J].中国循证医学杂志,2019, 19(4):78-86.
[6] 郭乐,李虹烨,罗洁.舒芬太尼和纳布啡复合丙泊酚在无痛胃肠镜麻醉中的临床研究[J].齐齐哈尔医学院学报,2019,40(10):1232-1233.
[7] 谭健安. 小剂量舒芬太尼复合丙泊酚用于无痛胃镜治疗的麻醉效果[J].临床合理用药,2021,14(1):79-80.
[8] 郑景丹,郑荣珍.不同给药方法阿芬太尼与舒芬太尼在120例全身麻醉诱导时诱发咳嗽情况观察[J].延边大学医学学报,2020,43(3):203-204.
[9] 李子超,肖洪一,朱腾,等.阿芬太尼复合丙泊酚在日间宫腔镜手术麻醉中的应用效果观察[J].山东医药,2022,62(6):72-75.
[10] 黄亚茹,丁宝苑,仪福霞,等.阿芬太尼复合丙泊酚麻醉在无痛胃肠镜检查中的麻醉效果观察[J]. 潍坊医学院学报. 2021,43(1):64-66.
[11] 王国庆. 阿芬太尼与舒芬太尼辅助丙泊酚持续静脉泵注在无痛肠镜检查中的麻醉效果比较[J]. 检验医学与临床,2022,2(19):405-408.
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