《中国期刊全文数据库》收录期刊
《中国核心期刊(遴选)数据库》收录期刊
《中文科技期刊数据库》收录期刊
论著

以1∶1比例输注新鲜冰冻血浆和去白悬浮红细胞对严重创伤急诊患者的影响

  • 张少丰 ,
  • 陈楚填 ,
  • 陈醒霞
展开
  • 1.东莞市厚街医院输血科, 广东 东莞 523945;
    2.东莞市厚街医院麻醉科, 广东 东莞 523945
张少丰(1980—),男,大学本科,副主任技师,从事临床输血科工作;电子信箱:zhangghong83@163.com

收稿日期: 2023-02-20

  网络出版日期: 2023-09-08

基金资助

2022年东莞市社会发展科技项目(20221800903872)

Effect of 1:1 infusion of fresh frozen plasma and leukocyte-removed suspended red blood cells on emergency patients with severe trauma

  • ZHANG Shaofeng ,
  • CHEN Chutian ,
  • CHEN Xingxia
Expand
  • 1. Blood Transfusion Department, Dongguan Houjie Hospital, Dongguan 523945, Guangdong, China;
    2. Anesthesia Department, Dongguan Houjie Hospital, Dongguan 523945, Guangdong, China

Received date: 2023-02-20

  Online published: 2023-09-08

摘要

目的 探讨以1∶1的比例输注新鲜冰冻血浆和去白悬浮红细胞对严重创伤急诊患者血栓弹力图指标和预后转归的影响。方法 选取收治的120例严重创伤行急诊输血患者,将其按照输注新鲜冰冻血浆和去白悬浮红细胞比例的不同分为1∶1比例输注治疗组、1∶2比例输注治疗组、1∶3比例输注治疗组,每组均40例。输注后,比较三组血栓弹力图指标[凝固角(α-Angle)、输血后凝固时间(K)值、反应时间(R)值以及血栓最大幅度(MA)值],并记录术后24 h出血量、重症监护病房(ICU)住院时间、休克纠正时间以及血容量恢复时间。结果 输注后,1∶1比例输注治疗组的α-Angle、MA值高于1∶2、1∶3比例输注治疗组,K值、R值较1∶2、1∶3比例输注治疗组低(P<0.05);1∶1比例输注治疗组的ICU住院时间、休克纠正时间以及血容量恢复时间均较1∶2、1∶3比例输注治疗组短(P<0.05)。结论 为严重创伤急诊患者以1∶1的比例输注新鲜冰冻血浆和去白悬浮红细胞可有效改善其凝血状态,并为其预后的改善提供积极助力,其应用效果值得肯定。

本文引用格式

张少丰 , 陈楚填 , 陈醒霞 . 以1∶1比例输注新鲜冰冻血浆和去白悬浮红细胞对严重创伤急诊患者的影响[J]. 外科研究与新技术(中英文), 2023 , 12(2) : 112 -114 . DOI: 10.3969/j.issn.2095-378X.2023.02.009

Abstract

Objective To investigate the effect of 1∶1 infusion of fresh frozen plasma and leukocyte-removed suspended red blood cells on the indexes of thromboelastogram and prognosis of severe trauma emergency patients. Methods A total of 120 patients with severe trauma undergoing emergency blood transfusion were prospectively collected and divided into 1∶1 proportional infusion treatment group, 1∶2 proportional infusion treatment group, and 1∶3 proportional infusion treatment group according to different proportions of fresh frozen plasma infusion and leukocyte-removed suspended red blood cell infusion, 40 patients in each group. After infusion, comparisons were made among the three groups of thromboelastogram indexes [coagulation angle (α-Angle), coagulation time (K) after blood transfusion, reaction time (R), and maximum thrombus amplitude (MA)], as well as recording of the amount of bleeding 24 h after operation, the length of stay in intensive care unit (ICU), the time to correct shock, and the time to recover blood volume. Results After infusion, the α-Angle and MA of the 1∶1 proportional infusion treatment group were higher than those of the 1∶2 and 1∶3 proportional infusion treatment groups, while the values of K and R were lower (P<0.05). The ICU hospitalization time, shock correction time, and blood volume recovery time of the 1∶1 proportional infusion treatment group were shorter than those of the 1∶2 and 1∶3 proportional infusion treatment groups (P<0.05). Conclusion Infusion of fresh frozen plasma and leukocyte-removed suspended red blood cells at a ratio of 1∶1 for emergency patients with severe trauma can effectively improve their coagulation state and provide positive assistance for their prognosis, and its application effect is worthy of affirmation.

参考文献

[1] 曾显莹. 新鲜冰冻血浆与红细胞高比例输注对严重创伤大量输血患者凝血功能及免疫功能的影响[J].实用中西医结合临床,2021,21(19):116-117.
[2] 冉小利,吴朋,刘宿.自体血液回输应用于严重创伤失血性休克患者救治的研究进展[J].创伤外科杂志,2022,24(10):393-398.
[3] 蔡纪坡. 新鲜冰冻血浆与红细胞悬液等比例输注对严重创伤出血患者疾病转归的影响[J].医学理论与实践,2021,34(20):3551-3553.
[4] 江光荣,周炜,邬俊勇.血栓弹力图对严重创伤后出血患者输血治疗的指导价值[J].当代医学,2021,27(21):168-170.
[5] 张玲,樊秀敏,康芳芳.输注冷沉淀的时间对严重创伤性失血患者的影响[J].临床医学研究与实践,2020,5(33):70-72.
[6] 王琦,李立宏,田小溪,等.血栓弹力图和凝血功能指标在严重创伤性患者中的变化及临床意义[J].海南医学,2020,31(21):2790-2792.
[7] 李明明. 血浆和红细胞不同比例在大量输血患者中应用效果分析[J].实验与检验医学,2020,38(2):404-408.
[8] 曾庆波,宋景春,胡炜,等.严重创伤时应用血栓弹力图指导血小板输注指征的临床研究[J].中国输血杂志,2019,32(10):1004-1007.
文章导航

/