目的 探析在早期甲状腺乳头状癌中采用经胸-乳入路腔镜甲状腺癌根治术（ERT）的效果及对患者应激指标、甲状腺功能和甲状旁腺功能的影响。方法 选取2020年1月—2023年1月诊治的62例早期甲状腺乳头状癌患者为研究对象,根据随机数字表法分为对照组和观察组,每组各31例。对照组常规手术治疗,观察组经胸-乳入路ERT治疗。比较两组甲状腺功能、甲状旁腺功能[促甲状腺激素（TSH）、甲状腺激素（T₄）、三碘甲状腺原氨酸（T₃）、甲状旁腺素（PTH）]及应激指标[皮质醇（Cor）、超氧化物歧化酶（SOD）、去甲肾上腺素（NE）]水平。结果 术后,观察组T₃、T₄、PTH、SOD水平高于对照组（P>0.05）;观察组Cor、NE、TSH水平低于对照组（P<0.05）。结论 在早期甲状腺乳头状癌中采用经胸-乳入路ERT治疗,可减轻患者应激反应,维持甲状腺及甲状旁腺功能。

Objective To explore the effectiveness of endoscopic radical thyroidectomy （ERT） through the chest breast approach on early papillary thyroid cancer and its impact on patient stress indicators, thyroid function, and parathyroid function. Methods From January 2020 to January 2023, a total of 62 patients with early papillary thyroid cancer diagnosed and treated in the hospital were selected as study subjects. They were randomly divided into a control group and an observation group by random number table method, with 31 cases per group. The control group received routine surgical treatment, while the observation group received ERT treatment through the chest breast approach. The thyroid function, parathyroid function （thyroid stimulating hormone （TSH）, thyroid hormone （T₄）, triiodothyronine （T₃）, and parathyroid hormone （PTH））, and stress indicators （cortisol （Cor）, superoxide dismutase （SOD）, and norepinephrine （NE）） were compared between the two groups. Results After operation, the levels of T₃, T₄, PTH, and SOD in the observation group were higher than those in the control group （P>0.05）; the levels of Cor, NE, and TSH in the observation group were lower than those in the control group （P<0.05）. Conclusion The use of transthoracic breast approach ERT treatment for early papillary thyroid cancer can reduce stress response and maintain thyroid and parathyroid functions of patients.