目的 探讨先天性甲状腺偏侧缺如合并Graves病和甲状腺结节患者的临床特征、发病机制、诊疗情况。方法 回顾性分析1例右侧甲状腺腺叶缺如合并Graves病和左侧甲状腺结节患者的临床表现、实验室/辅助检查及诊疗过程,并复习相关文献。结果 患者因甲状腺功能亢进症就诊,甲状腺功能和甲状腺摄碘-131试验结果提示Graves病;甲状腺超声检查提示右侧甲状腺腺叶缺如合并左侧甲状腺结节（TI-RADs Ⅳb级）。予以抗甲状腺药物甲巯咪唑治疗,甲状腺功能控制良好,甲状腺结节密切随访中。结论 同时合并先天性甲状腺偏侧缺如、Graves病和甲状腺结节的病例极其罕见,通过该病例的分析和相关文献复习,可为这类患者的诊疗积累宝贵经验。
Objective To investigate the clinical characteristics, pathogenesis, diagnosis, and treatment of patients with congenital thyroid hemiagenesis （TH） complicated with Graves’ disease and thyroid nodule. Methods A retrospective analysis was conducted on a patient with right TH associated with Graves’ disease and left thyroid nodule, and relevant literature was reviewed. Results A patient presented to the clinic with hyperthyroidism. Thyroid function examination and thyroid 131I uptake test suggested Graves’ disease. Thyroid ultrasound scan demonstrated absence of the right lobe with left thyroid nodule （TI-RADs Ⅳb）. Methimazole was used to control hyperthyroidism and thyroid nodule were followed. Conclusion The combination of TH, Graves’ disease, and thyroid nodule is extremely rare. A better comprehension of such patients through case report and literature review is essential for clinical intervention.
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