目的 探析在胃癌患者中采用不同入路方式的腹腔镜胃癌根治术治疗对胃肠功能及血清炎性因子水平的影响。方法 选取2019年7月—2022年7月诊治的120例胃癌患者,根据随机数字表法将其分为对照组和观察组,每组各60例。两组均行腹腔镜胃癌根治术,其中对照组从左侧后入路,观察组从右侧前入路。对比两组术前术后胃肠功能评分、血清炎性因子[白细胞介素-6（IL-6）、超敏C反应蛋白（hs-CRP）]水平。结果 观察组术后胃肠功能评分均较术前下降且低于对照组（P<0.05）;观察组术后IL-6、hs-CRP水平低于对照组（P<0.05）。结论 在胃癌患者中以右侧前入路行腹腔镜胃癌根治术,炎性反应较轻,有利于胃肠功能恢复。

Objective To explore the effects of laparoscopic radical gastrectomy with different approaches on gastrointestinal function and serum inflammatory factor levels in patients with gastric cancer. Methods A total of 120 gastric cancer patients diagnosed and treated from July 2019 to July 2022 were selected and divided into a control group and an observation group according to random number table method, with 60 cases in each group. Both groups underwent laparoscopic radical gastrectomy, in which the control group underwent a left posterior approach and the observation group underwent a right anterior approach. Gastrointestinal function scores and serum inflammatory factor [interleukin-6 （IL-6）, hypersensitive C-reactive protein （hs-CRP）] levels were compared between the two groups before and after surgery. Results Postoperative gastrointestinal function scores of the observation group were lower than preoperative scores and those of the control group （P<0.05）. The levels of IL-6 and hs-CRP in the observation group were lower than those in the control group （P<0.05）. Conclusion Laparoscopic radical gastrectomy with right anterior approach can reduce inflammatory reaction and promote gastrointestinal function recovery in patients with gastric cancer.