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外科研究与新技术 ›› 2023, Vol. 12 ›› Issue (4): 273-275.doi: 10.3969/j.issn.2095-378X.2023.04.010

• 论著 • 上一篇    下一篇

腹腔镜输卵管开窗取胚术治疗异位妊娠对患者卵巢储备功能和再次妊娠的影响

李妙力, 连丽珊   

  1. 厦门市第五医院妇科, 福建 厦门 351101
  • 收稿日期:2023-05-24 出版日期:2023-11-28 发布日期:2024-01-17
  • 作者简介:李妙力(1989—),女,大学本科,主治医师,从事异位妊娠或特殊类型的妊娠工作;电子信箱:lizhihaidg@163.com

Impact of laparoscopic fallopian tube fenestration and embryo retrieval surgery on ovarian reserve function and re-pregnancy in patients with ectopic pregnancy

LI Miaoli, LIAN Lishan   

  1. Department of Gynaecology, Xiamen Fifth Hospital, Xiamen 351101, Fujian, China
  • Received:2023-05-24 Online:2023-11-28 Published:2024-01-17

摘要: 目的 分析腹腔镜输卵管开窗取胚术治疗异位妊娠的临床疗效,并探究该术式对患者卵巢储备功能和再次妊娠的影响。方法 选取2020年1月—2023年1月收治的86例异位妊娠患者作为研究对象,按患者住院号单双数分为对照组(单数)和观察组(双数)各43例。对照组实施患侧输卵管切除术,观察组给予腹腔镜下开窗取胚术。比较两组患者手术前后血清抗米勒管激素水平、术后窦卵泡数量、术后再次妊娠率。结果 术前,不同年龄阶段的两组患者血清抗米勒管激素水平对比,差异无统计学意义(P>0.05);术后3个月,20~30岁、31~35岁的观察组患者血清抗米勒管激素水平高于对照组(P<0.05);术后6个月,20~30岁、31~35岁阶段的两组患者血清抗米勒管激素水平比较,差异无统计学意义(P>0.05)。观察组术后3个月、术后6个月的窦卵泡数量多于对照组,差异有统计学意义(P<0.05)。观察组术后12个月宫内妊娠率高于对照组、不孕率低于对照组(P<0.05)。结论 采用腹腔镜输卵管开窗取胚术治疗异位妊娠患者可以保护卵巢储备功能与生殖功能,有助于患者术后再次宫内妊娠率提升。

关键词: 腹腔镜输卵管开窗取胚术, 异位妊娠, 卵巢储备功能, 再次妊娠

Abstract: Objective To analyze the clinical efficacy of laparoscopic fallopian tube fenestration and embryo retrieval surgery for ectopic pregnancy, and to explore its impact on ovarian reserve function and re-pregnancy in patients. Methods A total of 86 patients with ectopic pregnancy admitted from January 2020 to January 2023 were selected as research subjects, and divided into a control group (odd number) and an observation group (even number) with 43 patients in each group, based on their admission numbers. The control group underwent salpingectomy on the affected side, while the observation group underwent laparoscopic fenestration and embryo retrieval. The levels of serum anti-Mullerian hormone before and after surgery, the number of postoperative sinus follicles after surgery, and the rate of postoperative re-pregnancy were compared between the two groups of patients. Results Before surgery, there was no statistically significant difference in serum levels of anti-Mullerian hormone between the two groups of patients of different age groups (P>0.05). At 3 months after surgery, the serum levels of anti-Mullerian hormone in the observation group aged 20-30 and 31-35 years were higher than those in the control group (P<0.05). At 6 months after surgery, there was no statistically significant difference in the serum levels of anti-Mullerian hormone between the two groups of patients aged 20-30 and 31-35 years (P>0.05). The number of sinus follicles in the observation group was higher than that in the control group at 3 and 6 months after surgery (P<0.05). The intrauterine pregnancy rate in the observation group was higher than that in the control group at 12 months after surgery, and the infertility rate was lower (P<0.05). Conclusion Laparoscopic fallopian tube fenestration and embryo retrieval surgery can protect ovarian reserve function and reproductive function in patients with ectopic pregnancy, and help improve the rate of intrauterine re-pregnancy after surgery.

Key words: Laparoscopic fenestration of fallopian tube and embryo retrieval, Ectopic pregnancy, Ovarian reserve function, Re-pregnancy

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