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外科研究与新技术(中英文) ›› 2026, Vol. 15 ›› Issue (1): 1-5.doi: 10.3969/j.issn.2095-378X.2026.01.001

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中西医结合治疗骨折延迟愈合及不愈合临床研究进展

杨庆, 王庚启   

  1. 上海中医药大学附属岳阳中西医结合医院创伤骨科,上海 200437
  • 收稿日期:2026-03-09 出版日期:2026-03-28 发布日期:2026-04-21
  • 通讯作者: 王庚启,电子信箱:wanggengqi@126.com
  • 作者简介:杨庆(1982—),男,博士,副主任医师,从事临床创伤骨科工作
  • 基金资助:
    上海市中医药研究院科技发展项目(24YJS15); 岳阳医院“揭榜挂帅”转化医学研究基金接骨木康方治疗老年髋部骨折前瞻性临床研究(2024YJJB05)

Clinical research progress on integrated traditional Chinese and Western medicine in treatment of delayed union and nonunion of fractures

YANG Qing, WANG Gengqi   

  1. Department of Orthopaedic Trauma, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China
  • Received:2026-03-09 Online:2026-03-28 Published:2026-04-21

摘要: 骨折延迟愈合或不愈合是骨折治疗后常见的严重并发症,单纯西医或中医单一治疗模式均存在明显局限。近年来,中西医结合治疗骨折延迟愈合或不愈合呈现精准化、多元化发展态势,在治疗方案优化、疗效机制阐释、新型技术研发等方面取得突破性进展。其治疗方案持续向分型施策、协同增效方向完善,基于不同类型骨折延迟愈合或不愈合的病理特点,制定个性化干预方案,其中中药联合西医固定、生物制剂及细胞治疗等相关技术的干预方式疗效确切,可有效加快骨痂生长速度、缩短骨折愈合周期。新型技术研发聚焦中西医前沿技术的深度融合,进一步丰富了临床治疗选择、提升了治疗效果,为精准诊疗提供了坚实支撑。本文结合相关研究成果及荟萃分析结论,系统梳理中西医结合治疗骨折延迟愈合或不愈合的核心进展,凸显其协同治疗优势,为临床诊疗工作提供参考依据。

关键词: 骨折, 延迟愈合, 不愈合, 中西医结合, 临床研究

Abstract: Fracture delayed union or nonunion is a serious complication after fracture treatment, and both simple Western medicine and traditional Chinese medicine (TCM) treatments have obvious limitations. In recent years, the integrated TCM and Western medicine treatment for fracture delayed union or nonunion has shown a precise and diversified development trend, achieving breakthrough progress in treatment regimen optimization, mechanism of action, and new technology research and development. The treatment regimens are continuously optimized towards classification-based management and synergistic efficacy, and personalized intervention plans are formulated according to different types of fracture delayed union or nonunion. Among them, interventions combining TCM with Western medical fixation, biological agents, cell therapy, and other related technologies have significant curative effects, and can effectively accelerate callus growth and shorten fracture healing time. The research and development of new technologies focuses on the integration of cutting-edge TCM and Western medicine technologies, further enriching treatment options, improving treatment outcomes, and providing solid support for precise treatment. Based on relevant research results and meta-analysis conclusions, this article systematically reviewed the core progress of integrated TCM and Western medicine in the treatment of fracture delayed union or nonunion, highlighting its synergistic advantages, and providing a reference for clinical diagnosis and treatment.

Key words: Fracture, Delayed union, Nonunion, Integrated traditional Chinese and Western medicine, Clinical research

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