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外科研究与新技术 ›› 2015, Vol. 4 ›› Issue (4): 233-234.

• 论著 • 上一篇    下一篇

分析卡培他滨联合奥沙利铂治疗老年胃癌患者的临床疗效

慕竹青   

  1. 新乡中心医院
  • 收稿日期:2015-11-13 修回日期:2015-11-09 出版日期:2015-12-28 发布日期:2016-01-05
  • 通讯作者: 慕竹青 E-mail:llliulinxx@163.com

Clinical effect of capecitabine combined with oxaliplatin in treating elderly patients with gastric cancer

  • Received:2015-11-13 Revised:2015-11-09 Online:2015-12-28 Published:2016-01-05

摘要: 【摘要】目的:对奥沙利铂与卡培他滨联合在老年胃癌治疗中取得的临床效果进行分析探讨。方法:研究对象为2014年10月至2015年,选取我院120例接受治疗的老年胃癌患者,随机分为对照组(60例患者采用5-氟尿嘧啶与奥沙利铂联合治疗)和试验组(60例患者采用卡培他滨与奥沙利铂联合治疗),对比分析两组患者的效果和并发症的发生概率。结果:试验组患者的总有效率(54例,90.00%)明显比对照组患者的总有效率(39例,65.00%)高,通过比较患者肝功能异常、恶心呕吐、白细胞减少、感觉神经异常、血小板减少、口腔黏膜细胞等并发症,发现试验组各种并发症的发生概率明显低于对照组患者各种并发症的发生概率,统计学上有意义(P<0.05)。结论:在治疗老年胃癌中采用奥沙利铂与卡培他滨联合的临床效果较好,并发症发生概率较低,值得临床上大力推广。

关键词: 【关键词】卡培他滨, 奥沙利铂, 胃癌, 临床疗效

Abstract: Abstract Objective: To investigate the clinical effect of capecitabine combined with oxaliplatin in treating elderly patients with gastric cancer. Methods: 120 elderly patients with gastric cancer in our hospital from October 2014 to October 2015 were selected. They were divided into control group (n=60, given 5-fluorouracil combined with oxaliplatin) and observation group (n=60, given capecitabine combined with oxaliplatin). Results: Total efficiency of observation group (n=54, 90.00%) was obviously higher than control group (n=39,65.00%). Compared the abnormal liver function, nausea and vomiting, leukopenia, abnormal sensory nerve, thrombocytopenia and buccal cell of the two groups. Incidence of complications of observation group was obviously lower than control group, the difference was statistically significant (P<0.05). Conclusion: Capecitabine combined with oxaliplatin in treating elderly patients with gastric cancer has better clinical effect, the incidence of complications is lower and is worthy of clinic application.

Key words: Key words: capecitabine, oxaliplatin, gastric cancer, clinic effect