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外科研究与新技术 ›› 2016, Vol. 5 ›› Issue (4): 267-270.

• 论著 • 上一篇    下一篇

骨化性气管支气管病临床病理特点并文献复习

周红1,朱旭友2,易祥华3,梁军2,宇小婷4,顾俊2,张龙4   

  1. 1. 上海市嘉定区南翔医院病理科
    2. 同济医院,病理科
    3. 上海市同济医院
    4. 上海市同济医院 同济大学附属同济医院病理科
  • 收稿日期:2016-08-12 修回日期:2016-08-31 出版日期:2016-12-28 发布日期:2017-02-17
  • 通讯作者: 朱旭友 E-mail:tjzxy1210@163.com

Traeheobrochopathia osteochondroplastica: clinicopathologicalfeatures and literature review

  • Received:2016-08-12 Revised:2016-08-31 Online:2016-12-28 Published:2017-02-17

摘要: [摘要] 目的 探讨骨化性气管支气管病的临床病理特点。方法 回顾性分析1例骨化性气管支气管病患者的临床、实验室检查、影像学及病理学特征并文献复习。结果 骨化性气管支气管病临床表现无特异性,高分辨CT扫描前、侧壁可见点状高密度影,后壁(膜部) 无高密度影,气管镜表现为支气管开口处见多发结节病灶,结节病理活检示粘膜下骨化、慢性炎症细胞浸润,表面呼吸上皮鳞状上皮化生伴轻度不典型增生。结论 骨化性气管支气管病比较少见,高分辨CT具有提示意义,支气管镜下表现具有特征性,其确诊需结合病理活检。

关键词: 骨化性气管支气管病, 诊断, 支气管镜

Abstract: [Abstract] Objective To explore the clicicopathologic features of traeheobrochopathia osteochondroplastica (TO). Methods The clinical, laboratory analysis and radiologic features of one TO case were analyzed retrospectively and the related literatures were reviewed. Results Clinical manifestations of TO were not specific. Results of high resolution CT of TO[基金项目:上海市同济医院青年基金项目资助(TJ1518) 作者简介:周红(1974-),女,副主任医师,研究方向:消化道病理诊断 通信作者:朱旭友,电子信箱:tjzxy1210@163.com] showed point like high density shadow of anterior and side wall , which were not existed in paries posterior (abdominal) . Bronchoscopy showed multiple nodules at the opening of the bronchus. Biopsy of the nodule showed submucosal ossification, lymphocyte infiltration and squamous metaplasia of the Surface respiratory epithelium with mild atypical hyperplasia .Conclusion TO is a rare disease. High resolution CT has significant clue to the diagnosis and bronchoscopy revealed characteristics. Its diagnosis should combined with pathological biopsy.

Key words: Traeheobrochopathia Osteochondroplastica, Diagnosis, Bronchoscopy