目的：探讨食管癌合并脉管瘤栓患者的临床病理特点。方法：回顾性分析535例食管癌患者的病理资料及临床特点。结果：535例食管癌患者中有125例发现脉管瘤栓。肿瘤低分化较高分化更易发生脉管瘤栓，统计有显著性意义（P?0.01）；肿瘤浸润深度越深，淋巴结转移数目越多，脉管瘤栓发生率越高，统计有显著性意义（P?0.01）。单因素分析结果显示，脉管瘤栓、肿瘤分化程度、肿瘤浸润深度、淋巴结分期均对患者预后有影响（P?0.01）。结论：食管癌脉管瘤栓与肿瘤的分化程度、浸润深度及淋巴结转移数目有相关关系。脉管瘤栓是影响食管癌患者预后的危险因素。
Objective: To investigate the clinical pathological characteristics of esophageal carcinoma complicated with vascular tumor embolus (VTE). Methods: The pathological data and clinical features of 535 patients with esophageal carcinoma were analyzed retrospectively. Results: There were 125 cases with VTE among 535 cases of esophageal carcinoma. The VTE is more likely to occur in poorly differentiated tumors than in high differentiated tumors, the difference is statistically significant（P?0.01）. The occurrence of VTE was closely related to the depth of tumor invasion and the number of lymph node metastasis, the statistics have significant（P?0.01）.The univariate regression analysis showed that VTE, the degree of tumor differentiation, the depth of invasion and lymph node staging were prognostic factors of patients with esophageal cancer. Conclusions: There is obvious relationship among the degree of tumor differentiation, the depth of invasion and the number of lymph node metastasis for VTE in esophageal cancer. VTE is a risk factor for prognosis of esophageal carcinoma.
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