[1] Couri T, Pillai A.Goals and targets for personalized therapy for HCC[J]. Hepatol Int, 2019, 13(2): 125-37.
[2] Bray F, Ferlay J, Soerjomataram I, et al.Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin, 2018, 68(6): 394-424.
[3] Ferguson S W, Wang J, Lee C J, et al.The microRNA regulatory landscape of MSC-derived exosomes: a systems view[J]. Sci Rep, 2018, 8(1): 1419.
[4] Bernal W.Acute liver failure: review and update[J]. Int Anesthesiol Clin,2017,55(2): 92-106.
[5] Sang W, Lu B, Li K, et al.Therapeutic efficacy and safety of umbilical cord mesenchymal stem cell transplantation for liver cirrhosis in Chinese population: a meta-analysis[J]. Clin Res Hepatol Gastroenterol,2018, 42(3): 193-204.
[6] Willis G R, Fernandez-gonzalez A, Anastas J, et al. Mesenchymal stromal cell exosomes ameliorate experimental bronchopulmonary dysplasia and restore lung function through macrophage immunomodulation[J]. Am J Respir Crit Care Med. 2018,197(1):104-116.
[7] Liang J, Zhang H, Zhao C, et al.Effects of allogeneic mesenchymal stem cell transplantation in the treatment of liver cirrhosis caused by autoimmune diseases[J]. Int J Rheum Dis,2017,20(9): 1219-26.
[8] Golpanian S, Wdf A, Hatzistergos K E, et al.Rebuilding the damaged heart: mesenchymal stem cells, cell-based therapy, and engineered heart tissue[J]. Physiol Rev, 2016, 96(3): 1127-68.
[9] Dominici M, Le Blanc K, Mueller I,et al.Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement[J]. Cytotherapy,2006,8(4): 315-317.
[10] Zhou P, Liu Z, Li X, et al.Migration ability and Toll-like receptor expression of human mesenchymal stem cells improves significantly after three-dimensional culture[J]. Biochem Biophys Res Commun,2017, 491(2): 323.
[11] Kojima Y, Tsuchiya A, Ogawa M, et al.Mesenchymal stem cells cultured under hypoxic conditions had a greater therapeutic effect on mice with liver cirrhosis compared to those cultured under normal oxygen conditions[J]. Regen Ther,2019,20(11): 269-281.
[12] Jiang H, Wang H, Liu T, et al.Co-cultured the MSCs and cardiomyocytes can promote the growth of cardiomyocytes[J]. Cytotechnology, 2018,70(2): 793-806.
[13] Li N, Hua J.Interactions between mesenchymal stem cells and the immune system[J]. Cell Mol Life Sci,2017,74(13): 2345-2360.
[14] Yin F, Wang W Y, Jiang W H.Human umbilical cord mesenchymal stem cells ameliorate liver fibrosis in vitro and in vivo: From biological characteristics to therapeutic mechanisms[J].World J Stem Cells,2019,11(8): 548-564.
[15] Tsuchiya A, Takeuchi S, Watanabe T, et al.Mesenchymal stem cell therapies for liver cirrhosis: MSCs as "conducting cells" for improvement of liver fibrosis and regeneration[J]. Inflamm Regen,2019,9(39):18.
[16] Lanthier N, Lin-marq N, Rubbia-brandt L, et al. Autologous bone marrow-derived cell transplantation in decompensated alcoholic liver disease: what is the impact on liver histology and gene expression patterns? [J]. Stem Cell Res Ther,2017,18:8(1):88.
[17] Qi X, Guo X, Su C.Clinical Outcomes of the transplantation of stem cells from various human tissue sources in the management of liver cirrhosis: a systematic review and meta-analysis[J]. Curr Stem Cell Res Ther,2015,10(2):166-180.
[18] Alfaifi M, Zom Y W, Newsome P N, et al.Mesenchymal stromal cell therapy for liver diseases[J]. J Hepatol, 2018, 68(6): 1272-1285.
[19] Fang X, Liu L, Dong J,et al.A study about immunomodulatory effect and efficacy and prognosis of human umbilical cord mesenchymal stem cells in patients with chronic hepatitis B-induced decompensated liver cirrhosis[J]. J Gastroenterol Hepatol,2018,33(4): 774-780.
[20] Lin B L, Chen J F, Qiu W H, et al.Allogeneic bone marrow-derived mesenchymal stromal cells for hepatitis B virus-related acute-on-chronic liver failure: a randomized controlled trial[J]. Hepatology,2017,66(1):209-219.
[21] Zhou X, Cui L, Zhou X, et al.Induction of hepatocyte-like cells from human umbilical cord-derived mesenchymal stem cells by defined microRNAs[J]. J Cell Mol Med, 2017, 21(5): 881-93.
[22] Zhang G Z, Sun H C, Zheng L B, et al.In vivo hepatic differentiation potential of human umbilical cord-derived mesenchymal stem cells: Therapeutic effect on liver fibrosis/cirrhosis[J]. World J Gastroenterol, 2017, 23(46): 8152-68.
[23] Sangiamsuntorn K, Hongeng S, Wongkajornsilp A.Development of hepatocyte-like cell derived from human induced pluripotent stem cell as a host for clinically isolated hepatitis C virus[J]. Curr Protoc Stem Cell Biol. 2017,14(42):1-4.
[24] Ewida S F, Abdou A G, El-rasiol Elhosary A A, et al. Hepatocyte-like versus mesenchymal stem cells in CCl4-induced liver fibrosis[J]. Appl Immunohistochem Mol Morphol, 2017, 25(10):736-745.
[25] 万思哲, 朱萱. 间充质干细胞对肝纤维化进展的调控机制[J].生命科学,2019,31(10):1054-1059.
[26] Yousefifard M, Nasirinezhad F, Shardi Manaheji H,et al.Human bone marrow-derived and umbilical cord-derived mesenchymal stem cells for alleviating neuropathic pain in a spinal cord injury model[J]. Stem Cell Res Ther, 2016,7(1):36.
[27] Luo X Y, Meng X J, Cao D C, et al.Transplantation of bone marrow mesenchymal stromal cells attenuates liver fibrosis in mice by regulating macrophage subtypes[J]. Stem Cell Res Ther, 2019,10(1):16.
[28] Wang M, Zhang M, Fu L, et al.Liver-targeted delivery of TSG-6 by calcium phosphate nanoparticles for the management of liver fibrosis[J]. Theranostics,2020,10(1):36-49.
[29] Jeong D, Han C, Kang I, et al.Effect of concentrated fibroblast-conditioned media on in vitro maintenance of rat primary hepatocyte[J]. PLoS One, 2016,11(2):1-14.
[30] Keshtkar S, Azarpira N, Ghahremani M H.Mesenchymal stem cell-derived extracellular vesicles: novel frontiers in regenerative medicine[J]. Stem Cell Res Ther, 2018, 9(1):63.
[31] Lou G, Chen Z, Zheng M, et al.Mesenchymal stem cell-derived exosomes as a new therapeutic strategy for liver diseases[J]. Exp Mol Med,2017,49(6):346.
[32] Phinney D G, Pittenger M F.Concise review: MSC-derived exosomes for cell-free therapy[J]. Stem Cells (Dayton, Ohio), 2017, 35(4):851-858.
[33] Lai R C, Yeo R W, Lim S K.Mesenchymal stem cell exosomes[J]. Semin Cell Dev Biol.2015, 40:82-88.
[34] Zhou X, Cui L, Zhou X, et al.Induction of hepatocyte-like cells from human umbilical cord-derived mesenchymal stem cells by defined microRNAs[J]. J Cell Mol Med, 2017, 21(5):881-893.
[35] Zhang S, Chuah S J, Lai R C, et al.MSC exosomes mediate cartilage repair by enhancing proliferation, attenuating apoptosis and modulating immune reactivity[J]. Biomaterials,2018,15(6):16-27.
[36] 肖帅,施宝民.干细胞诱导分化为肝细胞调控机制研究进展[J].外科研究与新技术,2017(3):47-50+55.
[37] Fiore E J, Dominguez L M, Bayo J, et al.Taking advantage of the potential of mesenchymal stromal cells in liver regeneration: cells and extracellular vesicles as therapeutic strategies[J]. World J Gastroenterol,2018,24(23):2427-2440.
[38] Wu P, Zahng B, Shi H, et al.MSC-exosome: a novel cell-free therapy for cutaneous regeneration[J]. Cytotherapy, 2018,20(3):291-301.
