Abstract: Objective To explore the impact of vacuum sealing drainage technology combined with muscle flap transfer and free skin grafting on the pain and appearance satisfaction of patients in the repair of refractory wounds. Methods A total of 88 patients with refractory wound repair admitted to the Second Hospital of Longyan from January 2022 to March 2024 were selected as research subjects. They were divided into an observation group and a control group according to the order of admission, with 44 patients in each group. Patients in the control group were treated with simple vaccum sealing drainage technology, while patients in the observation group were treated with a combination of vaccum sealing drainage technology, muscle flap transfer, and free skin grafting. After recording the data of the two groups during the study period, the clinical application value of each treatment method was compared and analyzed. Results During the treatment period, all indicators of the observation group were better than those of the control group （P<0.05）. The wound pain score of the observation group 1,3,7 d after treatment decreased compared to the control group （P<0.05）. Compared with the control group, the overall satisfaction with the appearance of the observation group increased （P<0.05）. Conclusion The combination of vaccum sealing drainage technology and free skin grafting with muscle flap transfer can improve clinical indicators, promote wound healing, reduce clinical pain, and increase appearance satisfaction in patients with refractory wound repair.

Key words: Vacuum sealing drainage, Muscle flap transfer and free skin grafting, Refractory wound repair, Wound pain, Appearance satisfaction