Abstract: Hemihepatectomy combined with caudate lobectomy: report of 31 cases Baomin Shi, Zhenhai Zhang, Zhongxue Su, Chengkun Qin, Jian Xu, Qingling Mu, Taihuang Wu Department of Hepatobiliary Surgery, Shandong Provincial Hospital of Shandong University, Jinan, 250021, China Objective: To explore the rationality and possibility of right or left hemihepatectomy combined with partial or whole caudate lobectomy and analyze its indications. Methods: Thirty-one patients surgically treated by hemihepatectomy combined with caudate lobectomy were retrospectively studied. The primary lesions included hepatocellular carcinoma(n=16), hilar cholangiocarcinoma(n=5), giant hemangioma(n=3), hepatolithiasis(n=4), hepatic metastasis(n=1), liver injury(n=1), hepatic inflammatory pseudotumor(n=2). Sixteen of the total were operated with right hemihepatectomy combined with caudate lobectomy and fifteen of them with left hemihepatectomy combined with caudate lobectomy. Result: The average operating time was 218±61 min(130min~367min). The average amount of blood loss was 350±283 ml(80ml~1100ml). Nineteen of the total were not given transfusion because their blood loss were less than 300ml during operation. The perioperative mortality was 0 and total morbidity was 35.5%(11/31), including pleural effusion(n=5), fat liquefaction of incision(n=2), slight hepatic encephalopathy(n=1), biliary leakage(n=3). All complications were treated successfully without operation. Conclusion: Liver lesions involving caudate lobe, either benign or malignant, could be safely and effectively by hemihepatectomy combined with partial or whole caudate lobectomy. Key words: hemihepatectomy, caudate lobectomy, morbidity, mortality