Abstract: Summary: Background: The aim of our study was to analyze diagnostic results, different treatment modalities, and the outcome of patients with breast abscesses, to determine whether minimally invasive treatments are successful. Methods: 110 patients with mastitis and suspected breast abscesses at our hospital between January 2013 and end of December 2015 were retrospectively analyzed. Using conservation, US-guided fine needle aspiration (FNA), and surgery treated the breast abscesses. Besides analysis the epidemiological risk factors for all patients. Results: 29% of the patients were treated with antibiotics only, 51% were treated with US-guided FNA or drainage placement. 20% of the patients underwent surgery. Early complications occurred in 7% of patients treated minimally invasive but not in patients treated with surgery alone. Late complications occurred in 5% of patients who underwent minimally invasive treatments and in 30% of patients who underwent surgery. Conclusions: US-guided FNA as a minimally invasive therapy in combination with antibiotics was found to successfully treat most breast abscesses and, in cases where a larger volume of pus was involved, the placement of an additional drainage catheter was effective.