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Surgical Research and New Technique ›› 2023, Vol. 12 ›› Issue (4): 237-242.doi: 10.3969/j.issn.2095-378X.2023.04.001

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Advances in systemic therapy of advanced renal cell carcinoma

HU Qingyue, ZHAI Wei, ZHENG Junhua   

  1. Department of Urology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
  • Received:2023-11-05 Online:2023-11-28 Published:2024-01-17

Abstract: Renal cell carcinoma is a common type of urinary cancer with insidious onset and rapid progression. Advanced renal cell carcinoma has poor prognosis and primarily depends on systemic therapy which mainly composed of targeted therapy and immunotherapy. Recently, new targeted drugs, immuno-targeted combination therapy, HIF-2α inhibitors, and probiotic combination therapy provide more possible options for the treatment. In this review, we gave an overview of the advances in systemic therapy of advanced renal cell carcinoma, aiming to help make clinical decisions.

Key words: Renal cell carcinoma, Systemic therapy, Targeted therapy, Immunotherapy

CLC Number: