Objective To investigate the curative effect of a new type of bioceramic iRoot single tip filling method on chronic apical periodontitis. Methods A total of 86 patients with chronic apical periodontitis treated from January 2022 to January 2025 were selected and divided into two groups according to different treatment methods, a control group （43 cases, AH-PLUS hot pressing glue filling） and an observation group （43 cases, iRoot SP single tip filling）. The effects of different treatment methods were evaluated by comparing the pain degree at 24 h and 7 d after operation, as well as the clinical efficacy and complications after 6 months of treatment between the two groups. Results Compared with the control group, the pain degree of the observation group was lower at 24 h after operation （P<0.05）, but there was no significant difference between the two groups at 7 d after operation （P>0.05）. After 6 months of treatment, the curative effect of the observation group was better than that of the control group （P<0.05）. There was no statistical difference in the incidence of complications between the two groups （P>0.05）. Conclusion The single tip filling method based on the new bioceramic iRoot can effectively reduce the early pain of patients with chronic apical periodontitis and improve the clinical curative effect.