Objective To investigate the clinical effect of minimally invasive extraction of impacted teeth with ultrasonic osteotome. Methods A total of 90 patients with impacted teeth in the maxilla and mandible who were treated in the Department of Stomatology of our hospital from January 2020 to December 2024 were selected as research participants. According to different treatment methods, the patients were divided into a control group with traditional tooth extraction method and a study group with ultrasonic osteotome minimally invasive method, with 45 cases in each group. The operation indexes, postoperative pain scores, postoperative mouth opening, and postoperative complications were compared between the two groups. Results The intraoperative blood loss in the study group was less than that in the control group （P<0.05）. The postoperative pain score of the study group was significantly lower than that of the control group （P<0.05）; the postoperative mouth opening degree of the study group was higher than that of the control group （P<0.05）; the incidence of postoperative complications in the study group was significantly lower than that in the control group （P<0.05）. Conclusion Compared with the traditional tooth extraction method, the ultrasonic osteotome minimally invasive method can reduce trauma to patients, intraoperative blood loss, postoperative pain, and complications, and also improve postoperative mouth opening restriction. The method is safe and effective, and has clinical value.