Objective To investigate the effect of bundled rehabilitation care combined with bladder function training in patients with neurogenic bladder due to spinal cord injury. Methods Patients with neurogenic bladder following spinal cord injury were divided into a control group （receiving conventional rehabilitation care） and an observation group （receiving bundled rehabilitation care plus bladder training）, with 72 cases in each group. There were no statistically significant differences between the two groups of patients in terms of gender ratio, age, and American Spinal Injury Association （ASIA） grading composition at baseline （P>0.05）. Comparisons were made in patients' psychological status [Self-Rating Anxiety Scale （SAS） scores/Self-Rating Depression Scale （SDS） scores], quality of life [Short-Form-36 Health Survey （SF-36） scores], as well as urinary function and incidence of urinary tract infections after 4 weeks of intervention with different nursing programs between the two groups. Results After 4 weeks of nursing care intervention, the observation group demonstrated lower SAS and SDS scores and higher SF-36 scores than the control group （P<0.05）. The observation group also showed lower detrusor pressure and residual urine volume, and higher maximum bladder capacity than the control group （P<0.05）. The results indicated that the observation group demonstrated superior psychological status, quality of life scores, and urinary function compared to the control group. Additionally, the incidence of urinary tract infections was significantly reduced in the observation group （4.76%, 2/72） than that in the control group （19.05%, 8/72） （P<0.05）. Conclusion The application of bundled rehabilitation care combined with bladder function training in patients with neurogenic bladder due to spinal cord injury effectively improves bladder function, reduces complication rates, and enhances patients' quality of life.