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Surgical Research and New Technique

Surgical Research and New Technique >

2013 , Vol. 2 >Issue 3: 180 - 184

DOI: https://doi.org/10.3969/j.issn.2095-378X.2013.03.013

Review

Progress of clinical application for N-terminal pro-brain natriuretic peptide in cardiac surgery

  • GU Chang ,
  • ZHANG Yang-yang
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  • 1.The First Clinical Medical College of Nanjing Medical University,Nanjing 210029,China;
    2.Department of Thoracic and Cardiovascular Surgery,the First Affiliated Hospital with Nanjing Medical University,Nanjing 210029,China

Online published: 2013-03-25

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Abstract

N-terminal pro-brain natriuretic peptide(NT-proBNP) is a kind of peptide which synthesized and secreted by ventricular muscle.When the stress of ventricular wall changes,NT-proBNP has an increasing secretion.NT-proBNP is recognized as a biomarker which can be used in the diagnosis of heart failure and prognosis prediction.Current studies have shown that NT-proBNP has clinical application value in the diagnosis and prognosis of coronary artery disease (CAD).The clinical value of NT-proBNP in cardiac surgery,especially in coronary artery bypass grafting (CABG) and cardiac valvular surgery gradually attracts popular’s attention.This article reviews the clinical application and research progress of NT-proBNP in cardiac surgery field.

Key words： N-terminal pro-brain natriuretic peptide; Coronary artery disease; Coronary artery bypass grafting; Cardiac valvular replacement

Cite this article

GU Chang , ZHANG Yang-yang . Progress of clinical application for N-terminal pro-brain natriuretic peptide in cardiac surgery[J]. Surgical Research and New Technique, 2013 , 2(3) : 180 -184 . DOI: 10.3969/j.issn.2095-378X.2013.03.013

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