Objective To evaluate the ultrasound diagnosis of diabetic lower limb vascular lesions and its clinical value.Methods From January to December 2016,patients with diabetic lower extremity vascular disease (n=50) admitted to Xuyi County People’s Hospital of Huai’an City were enrolled as observation group,and non-diabetic patients (n=50) were enrolled as control group.Both groups received lower extremity vascular color Doppler ultrasound,and the ultrasonographic features of the two groups were compared and analyzed.Results Of the 50 observation cases,47 cases (94%) had vascular injury.Specifically,the Doppler ultrasound examination results showed plaque in 41 cases (41/47,87.23%),stenosis in 14 cases (14/47,29.79%),and luminal occlusion in 11 cases (11/47,23.40%).Of the 50 control cases,22 cases (44%) had vascular injury.Specifically,the Doppler ultrasound examination results showed plaque in 13 cases (13/22,59.09%),stenosis in 4 cases (4/22,18.18%),and no vascular occlusion.The positive rates of lower extremity vascular injury,vascular plaque,stenosis,and luminal occlusion were significantly different betweent the two groups (P<0.05).According to the lower extremity vascular Doppler ultrasound imaging,compared with the control group,the observation group showed luminal stenosis,blood flow reduction,and spectrum width broadening.Conclusion Ultrasonography shows a high detection rate of lower extremity vascular injury.The simple and non-invasive precedure provides important imaging evidence for early diagnosis and treatment for the disease.