Objective To explore the clinical effects of CO2 laser for early glottic cancer.Methods The clinical data of 40 cases with early glottic cancer from May 2012 to May 2017 were selected, including 24 cases of T1a lesion, 9 cases of T1b lesion, 7 cases of T2 lesion, 34 cases without involvement of glottis joint, and 6 cases with involvement of glottis joint. After CO2 laser, the cases were followed up for 6-72 months.Results In the 40 cases, 5 cases (12.5%) recurred after surgery. The recurrence rates for T1a, T1b, and T2 lesion patients were 4.2%(1/24), 11.1%(1/9), and 42.9%(3/7), respectively (χ2=7.4376, P=0.0243). For the patients without involvement of glottis joint, the recurrence rate was 11.8% (4/34).For the patients with involvement of glottis joint, the recurrence rate was 16.7% (1/6) (χ2=0.1120, P=0.737 8). In the 40 cases, 39 (97.5%) cases survived and 1 died (2.5%).Conclusion CO2 laser can preserve voice function of larynx with good results for early glottic cancer, thus deserving promotion.
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