《中国期刊全文数据库》收录期刊
《中国核心期刊(遴选)数据库》收录期刊
《中文科技期刊数据库》收录期刊
Nursing

Nursing experience of 131I-chTNT radioimmunotherapy of 14 patients with advanced pancreatic cancer

  • PAN Minmin ,
  • YU Limin ,
  • LU Ying
Expand
  • Department of Interventional Therapy, Tongji Hospital Affiliated to Tongji University, Shanghai 200065, China

Received date: 2018-07-20

  Online published: 2019-12-16

Abstract

Objective To summarize the nursing key points of radioimmunotherapy of pancreatic cancer by observing the nursing care in 14 patients with advanced pancreatic cancer receiving injection of 131I-chTNT (iodine-131-lablbed tumor necrosis therapy chimeric antibody).Methods All pancreatic cancer patients (n=14) were treated with computed tomography(CT) guided 131I-chTNT intratumoral injection, and received comprehensive nursing including preoperative health education and postoperative complication nursing care.Results All patients were successfully treated with 131I-chTNT intratumoral injection with scientific, systematic, and meticulous nursing.The success rate was 100%.Specifically, 1 case had a complete response (CR) (7%), 4 cases achieved partial response (PR) (29%), 7 cases had stable conditions (50%), and 4 cases progressed (14%).The effective rate was 36%.Conclusions These promising Results demonstrate that sufficient doses of 131I-chTNT can be safely delivered to tumors to cause significant therapeutic effects on advanced pancreatic cancer.Perioperative psychological nursing, monitoring of vital signs, prevention and nursing of complications are a powerful guarantee for successful operation and prevention of complications.

Cite this article

PAN Minmin , YU Limin , LU Ying . Nursing experience of 131I-chTNT radioimmunotherapy of 14 patients with advanced pancreatic cancer[J]. Surgical Research and New Technique, 2018 , 7(3) : 218 -220 . DOI: 10.3969/j.issn.2095-378X.2018.03.018

References

[1] Siegel R, Naishadham D, Jemal A.Cancer statistics, 2012[J].CA Cancer J Clin, 2012, 62(1):10-29.
[2] Tse G, Chow DS, Hsu M, et al.Multidetector computed tomographic features of oncocytic papillary renal cell carcinoma a new subtype[J].J Comput Assist Tomogr, 2010, 34(6):380-384.
[3] 汤钊猷.现代肿瘤学[M].上海:复旦大学出版社, 2006:113.
[4] Reni M, Cordio S, Milandri C, et al.Gemcitabine versus cisplatin, epirubicin, fluorouracil, and gemcitabine in advanced pancreatic cancer: a randomized controlled multicentre phase Ⅲ trial[J].Lancet Oncol, 2005, 6:369-376.
[5] Kindler HL, Friberg G, Singh DA, et al.Phase Ⅱ trial of bevacizumab plus gemcitabine in patients with advanced pancreatic cancer[J].J Clin Oncol, 2005, 23(31):8033-8040.
[6] Mullaney T, Olausson K, Sharp L.The influence of a department’s psychosocial climate and treatment environment on cancer patients’ anxiety during radiotherapy[J].Eur J Oncol Nurs, 2016, 20(1):113-118.
[7] Aoyama T, Murakawa M, Katayama Y.Impact of postoperative complications on survival and recurrence in pancreatic cancer[J].Anticancer Res, 2015, 35(4):2401-2409.
[8] Illidge T, Johnson P.The emerging role of radioimmunotherapy in hematological malignancies[J].Br J Haematol, 2000, 108(4):679.
Outlines

/