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Surgical Research and New Technique

Surgical Research and New Technique >

2020 , Vol. 9 >Issue 2: 105 - 109

DOI: https://doi.org/10.3969/j.issn.2095-378X.2020.02.010

Review

Advances on treatment of liver diseases using mesenchymal stem cells

  • WEI Yuhua ,
  • SHI Baomin
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  • Department of General Surgery, Tongji Hospital Affiliated to Tongji University, Shanghai 200065, China

Received date: 2020-03-02

  Online published: 2020-09-16

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Abstract

Various acute and chronic liver diseases seriously affect human health, but there is still a lack of effective treatment methods. Mesenchymal stem cells (MSCs) are pluripotent stem cells with the potential for multidirectional differentiation. They come from a wide range of sources and have low immunogenicity in allotransplantation. They are widely used in the treatment of a variety of clinical diseases and have been proved effective. Nowadays, MSCs have also been used in the studies about the treatment of liver diseases, and some achievements have been made. However, the specific mechanism of MSCs in the treatment of diseases is still unclear, and how to improve its treatment effect and efficiency need to be solved. This review summarized the research advances on MSCs in the treatment of liver diseases, and discussed the application prospect of MSCs in the future.

Key words： Liver diseases; Mesenchymal stem cells; Mechanism; Exosome

Cite this article

WEI Yuhua , SHI Baomin . Advances on treatment of liver diseases using mesenchymal stem cells[J]. Surgical Research and New Technique, 2020 , 9(2) : 105 -109 . DOI: 10.3969/j.issn.2095-378X.2020.02.010

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