CircRNA is a kind of circular and closed-loop RNA. Because circRNA does not have 5′-end hat structure and 3′-end polyadenosine acidified tail structure, the expression of circRNA is more stable. As a hot spot in the field of RNA research, circRNA has been found to be associated with the occurrence of many diseases, including nervous system diseases, tumors, and diabetes. Infectious diseases refer to the local traumatic lesions and systemic inflammatory reactions related to impaired metabolic functions and tissue structures caused by the invasion, growth, and reproduction of bacteria, viruses, fungi, parasites and others in the human body. Current studies have proved that circRNA is associated with the occurrence of many infectious diseases. The paper reviewed the research progress on circRNA and infectious diseases.
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