Objective To explore the therapeutic effect of three-point balanced therapy on mixed hemorrhoids. Methods A total of 60 patients with mixed hemorrhoids from January 2019 to September 2020 were selected and divided into an observation group （30 cases, who received three-point balanced therapy） and a control group （30 cases, who received traditional external stripping and internal ligation） according to treatment methods. The clinical efficacy, incidence of complications, operation time, and recovery time of the two groups of patients were compared. Results After treatment, in the observation group, 25 cases were cured, 3 cases improved, and 2 cases failed. The total effective rate of the observation group was 93.33%, significantly higher than that of the control group （P<0.05）. After treatment, in the observation group, 1 patient had postoperative pain, 1 patient had anal incontinence, and 1 patient had anal edema, and the incidence rate of complications of the observation group was 10.00%, significantly lower than that of the control group （P<0.05）. After treatment, the operative time was （15.56±4.51） min and the wound healing time was （7.50±1.35） min of the observation group, significantly shorter than those of the control group （P<0.05）. Conclusion In the clinical treatment of mixed hemorrhoids, applying three-point balanced therapy can significantly improve the success rate of treatment, shorten the time of operation and wound healing, reduce the incidence of anal edema, anal incontinence, and postoperative pain, which is worthy of clinical reference.