Objective To explore the clinical effect of LVIS stent-assisted coil embolization on internal carotid artery-posterior communicating artery （ICA-PcoA） aneurysms. Methods A total of 210 patients with ICA-PcoA aneurysms admitted to our hospital and receiving stent-assisted coil embolization from March 2016 to March 2020 were divided into three groups according to different stents. Patients in the LVIS group （70 cases） were given LVIS stents, patients in the Solitare group （70 cases） were given Solitare stents, and patients in the Enterprise group （70 cases） were given Enterprise stents. The effect of stent-assisted embolization was assessed by digital subtraction angiography （DSA） and Raymond criteria. Prognostic effect was assessed using the Modified Rankin Scale （mRS） and the Activity of Daily Living Scale （BI index）. The incidence rate of surgical complications and the rate of recurrence of aneurysms were recorded. Results There was no significant difference in the success rate of stent placement among the three groups （χ²=1.032, P=0.479）. The Raymond grading showed that the embolization effect of aneurysms in the LVIS group was better than those in the Solidare group and the Enterprise group immediately after surgery and 6 months after surgery （all P<0.05）. The percentage of patients with 0-2 points of mRS score and BI index in the LVIS group were higher than those in the Solitare group and the Enterprise group after 6 months of surgery （all P<0.05）. The incidence rate of surgical complications and recurrence rate of aneurysms in the LVIS group were lower than those in the Solitare group and the Enterprise group, but there was no significant difference （all P>0.05）. Conclusion LVIS stent-assisted embolization has a good embolization effect on ICA-PcoA aneurysms, with high safety and low recurrence rate, but attention should be paid to intraoperative thrombosis and postoperative parent artery stenosis.