Objective To evaluate the anesthetic and postoperative analgesic of sufentanil combined with sevoflurane anesthesia in pediatric laparoscopic hernia surgery. Methods From January 2020 to June 2021, 100 pediatric laparoscopic hernia surgery patients were randomly assigned in accordance with random number table method into two groups. The control group adopted sufentanil, while the observation group used sufentanil combined with sevoflurane. Anesthesia-related indicators, postoperative Visual Analog Scale （VAS） scores, and the incidence of adverse reactions to anesthesia were compared between the two groups. Results The postoperative extubation time, anesthesia recovery time, spontaneous breathing recovery time in the observation group were shorter than those in the control group （P<0.05）. The VAS scores at different postoperative time points in the observation group were lower than those in the control group （P<0.05）. The adverse reaction rate in the observation group was significantly lower than that in the control group （P<0.05）. Conclusion Sufentanil combined with sevoflurane has a good analgesic effect, such as shortened anesthesia recovery time, reduced postoperative pain, and less adverse reactions, which is worthy of promotion.