Objective To explore the application of PDCA in improving the standard rate of emergency deployment equipment use in emergency rescue rooms. Methods PDCA cycle was applied to the management of emergency deployment equipment in emergency rescue rooms. A project quality improvement group was established based on the focus of current problems and cause analysis, and carried out continuous quality improvement according to the PDCA process of planning, doing, checking, and acting. Results The standard rate of emergency deployment equipment use in emergency rescue rooms increased from 76.25% before implementation to 95.00% after implementation, indicating that the nurses in rescue rooms improved their standard operation ability regarding emergency deployment equipment. Conclusion The application of PDCA can effectively improve the standard rate of emergency deployment equipment use of nurses in emergency rescue rooms, and ensure the safety of clinical nursing.