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Original article

Effect of 1:1 infusion of fresh frozen plasma and leukocyte-removed suspended red blood cells on emergency patients with severe trauma

  • ZHANG Shaofeng ,
  • CHEN Chutian ,
  • CHEN Xingxia
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  • 1. Blood Transfusion Department, Dongguan Houjie Hospital, Dongguan 523945, Guangdong, China;
    2. Anesthesia Department, Dongguan Houjie Hospital, Dongguan 523945, Guangdong, China

Received date: 2023-02-20

  Online published: 2023-09-08

Abstract

Objective To investigate the effect of 1∶1 infusion of fresh frozen plasma and leukocyte-removed suspended red blood cells on the indexes of thromboelastogram and prognosis of severe trauma emergency patients. Methods A total of 120 patients with severe trauma undergoing emergency blood transfusion were prospectively collected and divided into 1∶1 proportional infusion treatment group, 1∶2 proportional infusion treatment group, and 1∶3 proportional infusion treatment group according to different proportions of fresh frozen plasma infusion and leukocyte-removed suspended red blood cell infusion, 40 patients in each group. After infusion, comparisons were made among the three groups of thromboelastogram indexes [coagulation angle (α-Angle), coagulation time (K) after blood transfusion, reaction time (R), and maximum thrombus amplitude (MA)], as well as recording of the amount of bleeding 24 h after operation, the length of stay in intensive care unit (ICU), the time to correct shock, and the time to recover blood volume. Results After infusion, the α-Angle and MA of the 1∶1 proportional infusion treatment group were higher than those of the 1∶2 and 1∶3 proportional infusion treatment groups, while the values of K and R were lower (P<0.05). The ICU hospitalization time, shock correction time, and blood volume recovery time of the 1∶1 proportional infusion treatment group were shorter than those of the 1∶2 and 1∶3 proportional infusion treatment groups (P<0.05). Conclusion Infusion of fresh frozen plasma and leukocyte-removed suspended red blood cells at a ratio of 1∶1 for emergency patients with severe trauma can effectively improve their coagulation state and provide positive assistance for their prognosis, and its application effect is worthy of affirmation.

Cite this article

ZHANG Shaofeng , CHEN Chutian , CHEN Xingxia . Effect of 1:1 infusion of fresh frozen plasma and leukocyte-removed suspended red blood cells on emergency patients with severe trauma[J]. Surgical Research and New Technique, 2023 , 12(2) : 112 -114 . DOI: 10.3969/j.issn.2095-378X.2023.02.009

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