染色放大内镜在消化道早癌诊治中应用探讨

doi:10.3969/j.issn.2095-378X.2021.04.001

外科研究与新技术 ›› 2021, Vol. 10 ›› Issue (4): 237-241.doi: 10.3969/j.issn.2095-378X.2021.04.001

• 述评 • 下一篇

染色放大内镜在消化道早癌诊治中应用探讨

潘独伊, 毛奇琦, 钟良

复旦大学附属华山医院内镜中心,上海 200040

收稿日期:2021-12-08 出版日期:2021-12-28 发布日期:2022-08-22
通讯作者: 钟良,电子信箱：zhongniping@163.com
作者简介:潘独伊（1990—）,女,硕士研究生,主治医师,从事消化道早癌内镜诊治工作

Application of magnifying chromoendoscopy in diagnosis and treatment of early-stage gastrointestinal cancer

PAN Duyi, MAO Qiqi, ZHONG Liang

Department of Gastroenterology, Huashan Hospital Affiliated to Fudan University, Shanghai 200040, China

Received:2021-12-08 Online:2021-12-28 Published:2022-08-22

摘要/Abstract

摘要： 消化道早癌的早诊断早治疗能够显著改善患者的预后,而我国消化道早癌的检出率仍非常低,如何提高消化道早癌的检出率是当前面临的主要难题。本文旨在探讨染色放大内镜在消化道早癌诊治中临床应用的现状与前景。电子染色、光学染色与放大技术结合,能够识别胃黏膜微细结构和微血管的异常,明确病变性质及进展程度,并为精准的靶向活检指明方向。而放大内镜诊断与病理检查的相互结合,可为提高我国消化内镜精查、消化道早癌诊治提供更大帮助。

关键词: 染色放大内镜, 消化道早癌, 病理学习

Abstract: Early diagnosis and treatment of early-stage gastrointestinal cancer can significantly improve the prognosis of patients, but the detection rate of this disease in China is still very low. Therefore, how to improve the detection rate of early-stage gastrointestinal cancer is a major challenge at present. The Objective of this article is to explore the status quo and prospect of the application of magnifying chromoendoscopy in the diagnosis and treatment of early-stage gastrointestinal cancer. The combination of electronic staining, optical staining, and magnifying technology can identify the abnormality of gastric mucosa microstructure and microvessel, clarify the nature and progression of the lesion, and point out the direction of accurate targeted biopsy. The combination of magnifying endoscopy diagnosis and pathological examination can provide greater help than the individual techniques for improving the precise examination of digestive endoscopy and the diagnosis and treatment of early-stage gastrointestinal cancer in China.

Key words: Magnifying chromoendoscopy, Early-stage gastrointestinal cancer, Pathologic study

中图分类号:

R573

潘独伊, 毛奇琦, 钟良. 染色放大内镜在消化道早癌诊治中应用探讨[J]. 外科研究与新技术, 2021, 10(4): 237-241.

PAN Duyi, MAO Qiqi, ZHONG Liang. Application of magnifying chromoendoscopy in diagnosis and treatment of early-stage gastrointestinal cancer[J]. Surgical Research and New Technique, 2021, 10(4): 237-241.

参考文献

[1] Bray F, Ferlay J, Soerjomataram I, et al.Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin,2018,68(6):394-424.
[2] 陈万青,郑荣寿,曾红梅,等.2011年中国恶性肿瘤发病和死亡分析[J]. 中国肿瘤,2015,24(1):1-10.
[3] Tajiri H, Ohtsu A, Boku N, et al.Routine endoscopy using electronic endoscopes for gastric cancer diagnosis: retrospective study of inconsistencies between endoscopic and biopsy diagnoses[J]. Cancer Detect Prev,2001,25(2):166-173.
[4] Kawahara Y, Takenaka R, Okada H, et al.Novel chromo-endoscopic method using an acetic acid-indigocarmine mixture for diagnostic accuracy in delineating the margin of early gastric cancers[J]. Dig Endosc,2009,21(1):14-19.
[5] Dohi O, Yagi N, Yoshida S, et al.Magnifying blue laser imaging versus magnifying narrow-band imaging for the diagnosis of early gastric cancer: a prospective, multicenter, comparative study[J]. Digestion,2017,96(3):127-134.
[6] Sakaki N, Iida Y, Okazaki Y, et al.Magnifying endoscopic observation of the gastric mucosa, particularly in patients with atrophic gastritis[J]. Endoscopy,1978,10(4):269-274.
[7] Yao K, Anagnostopoulos GK, Ragunath K.Magnifying endoscopy for diagnosing and delineating early gastric cancer[J]. Endoscopy,2009,41(5):462-467.
[8] Nakayoshi T, Tajiri H, Matsuda K, et al.Magnifying endoscopy combined with narrow band imaging system for early gastric cancer: correlation of vascular pattern with histopathology (including video)[J]. Endoscopy,2004,36(12):1080-1084.
[9] Yagi K N A S A. Magnifying endoscopy with narrow band imaging for early differentiated gastric adenocarcinoma[J]. Dig Endosc,2008(20):115-122.
[10] 小山恒男. 早期胃癌内镜诊断的方法与策略[M]. 沈阳:辽宁科学技术出版社,2017:5-14.
[11] Kudo S, Hirota S, Nakajima T, et al.Colorectal tumours and pit pattern[J]. J Clin Pathol,1994,47(10):880-885.
[12] Goda K, Dobashi A, Yoshimura N, et al.Narrow-band imaging magnifying endoscopy versus lugol chromoendoscopy with pink-color sign assessment in the diagnosis of superficial esophageal squamous neoplasms: a randomised noninferiority trial[J]. Gastroenterol Res Pract,2015,2015:639462.
[13] Goda K, Tajiri H, Ikegami M, et al.Clinical impact of narrow-band imaging magnifying endoscopy for 'basal layer type squamous cell carcinoma' in the esophagus[J]. Dig Endosc,2011,23(Suppl 1):75-78.
[14] Shimizu Y, Takahashi M, Mizushima T, et al.Chromo-endoscopy with iodine staining, as well as narrow-band imaging, is still useful and reliable for screening of early esophageal squamous cell carcinoma[J]. Am J Gastroenterol,2015,110(1):193-194.
[15] 王鹏飞,陈兆峰,王鹏斌,等. 卢戈氏液染色与窄带成像放大内镜在早期食管癌术前诊断中的价值比较[J]. 中国内镜杂志,2016,22(9):20-24.
[16] 唐榛,杨亚玲,文黎明. 内镜窄带成像技术联合放大内镜诊断胃癌准确性的Meta分析[J]. 中国内镜杂志,2020,26(12):8-17.
[17] Doyama H, Nakanishi H, Yao K.Image-enhanced endoscopy and its corresponding histopathology in the stomach[J]. Gut Liver,2021,15(3):329-337.
[18] Horiuchi Y, Fujisaki J, Yamamoto N, et al.Accuracy of diagnostic demarcation of undifferentiated-type early gastric cancers for magnifying endoscopy with narrow-band imaging: endoscopic submucosal dissection cases[J]. Gastric Cancer,2016,19(2):515-523.
[19] Yamada S, Doyama H, Yao K, et al.An efficient diagnostic strategy for small, depressed early gastric cancer with magnifying narrow-band imaging: a post-hoc analysis of a prospective randomized controlled trial[J].Gastrointest Endosc,2014,79(1):55-63.
[20] Uedo N, Fujishiro M, Goda K, et al.Role of narrow band imaging for diagnosis of early-stage esophagogastric cancer: current consensus of experienced endoscopists in Asia-Pacific region[J]. Dig Endosc,2011,23(Suppl 1):58-71.
[21] Li H Y, Dai J, Xue H B, et al.Application of magnifying endoscopy with narrow-band imaging in diagnosing gastric lesions: a prospective study[J]. Gastrointest Endosc,2012,76(6):1124-1132.
[22] Kobara H, Mori H, Fujihara S, et al.Prediction of invasion depth for submucosal differentiated gastric cancer by magnifying endoscopy with narrow-band imaging[J]. Oncol Rep,2012,28(3):841-847.
[23] Backes Y, Moss A, Reitsma JB, et al.Narrow band imaging, magnifying chromoendoscopy, and gross morphological features for the optical diagnosis of t1 colorectal cancer and deep submucosal invasion: a systematic review and meta-analysis[J]. Am J Gastroenterol,2017,112(1):54-64.
[24] 张燕霞,黄茜,马久红. 染色放大内镜对早期胃癌诊断一致性的研究[J]. 广东医学,2016,37(S1):133-134.
[25] 赵俊军张秀梅罗亚岚陶晓峰付明杰. 内镜胃黏膜下剥离术前后病理诊断的差异分析[J]. 现代消化及介入诊断,2020,25(3):392-395.
[26] Ruffle JK, Farmer AD, Aziz Q.Artificial intelligence-assisted gastroenterology-promises and pitfalls[J]. Am J Gastroenterol,2019,114(3):422-428.
[27] Horiuchi Y, Hirasawa T, Ishizuka N, et al.Diagnostic performance in gastric cancer is higher using endocytoscopy with narrow-band imaging than using magnifying endoscopy with narrow-band imaging[J]. Gastric Cancer,2021,24(2):417-427.

染色放大内镜在消化道早癌诊治中应用探讨

Application of magnifying chromoendoscopy in diagnosis and treatment of early-stage gastrointestinal cancer

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 1

编辑推荐

Metrics

本文评价