袖状胃减容术对肥胖介导的男性生殖功能障碍的影响

doi:10.3969/j.issn.2095-378X.2024.04.018

外科研究与新技术（中英文） ›› 2024, Vol. 13 ›› Issue (4): 345-349.doi: 10.3969/j.issn.2095-378X.2024.04.018

袖状胃减容术对肥胖介导的男性生殖功能障碍的影响

陈伟玲¹, 相俊¹, 乐威¹, 王炎秋²

1.同济大学附属同济医院泌尿外科, 上海 200065;
2.同济大学附属同济医院生殖医学科, 上海 200065

收稿日期:2023-10-20 出版日期:2024-12-28 发布日期:2025-01-09
通讯作者: 相俊,电子信箱：sheyewood@163.com
基金资助:
上海市同济医院临床研究培训项目（ITJ（20）2310）

Effect of sleeve gastrectomy on obesity-mediated male reproductive dysfunction

CHEN Weiling¹, XIANG Jun¹, LE Wei¹, WANG Yanqiu²

1. Department of Urology, Tongji Hospital Affiliated to Tongji University, Shanghai 200065, China;
2. Department of Reproductive Medicine, Tongji Hospital Affiliated to Tongji University, Shanghai 200065, China

Received:2023-10-20 Online:2024-12-28 Published:2025-01-09

摘要/Abstract

摘要： 肥胖是导致高血压、高血脂、糖尿病的重要因素,同时也是导致男性生殖功能障碍,如男性肥胖继发性腺功能减退症、精子质量及性生活质量下降等的元凶之一。基于现实因素,减肥手术被越来越多的人所接受,且其效力对重度肥胖患者最为显著。袖状胃切除术作为如今主流的一种微创减肥手术方式,具有围手术期风险较小、术后减重效果良好等优点。本文综述了袖状胃切除术对肥胖介导的男性生殖功能障碍的影响,旨在为减肥手术的临床应用提供更多的参考依据。

关键词: 肥胖, 减肥, 袖状胃减容术, 男性生殖功能障碍

Abstract: Obesity is a major factor leading to hypertension, hyperlipidaemia and diabetes, as well as one of the causes of male reproductive dysfunction, such as male obesity secondary hypogonadism （MOSH）, reduced sperm quality, and reduced quality of sexual life. For practical reasons, bariatric surgery is becoming increasingly accepted, and it is most effective in severely obese patients. Sleeve gastrectomy, as the mainstay of minimally invasive bariatric surgery today, has the advantages of low perioperative risk and good postoperative weight loss effect. This paper reviewed the effect of sleeve gastrectomy on obesity-mediated male reproductive dysfunction, with the aim of providing more references for the clinical application of bariatric surgery.

Key words: Obesity, Weight loss, Sleeve gastrectomy, Male reproductive dysfunction

中图分类号:

陈伟玲, 相俊, 乐威, 王炎秋. 袖状胃减容术对肥胖介导的男性生殖功能障碍的影响[J]. 外科研究与新技术（中英文）, 2024, 13(4): 345-349.

CHEN Weiling, XIANG Jun, LE Wei, WANG Yanqiu. Effect of sleeve gastrectomy on obesity-mediated male reproductive dysfunction[J]. Surgical Research and New Technique, 2024, 13(4): 345-349.

参考文献

[1] Kelishadi R, Haghdoost AA, Sadeghirad B, et al.Trend in the prevalence of obesity and overweight among Iranian children and adolescents: a systematic review and meta-analysis[J]. Nutrition,2014, 30(4): 393-400.
[2] Mokdad AH, Ford ES, Bowman BA, et al.Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001[J]. JAMA, 2003, 289(1): 76-79.
[3] Olquitt JL, Pickett K, Loveman E, et al. Surgery for weight loss in adults [J]. Cochrane Database of Syst Rev, 2014, 2014(8): Cd003641.
[4] Arterburn DE, Telem DA, Kushner RF, et al.Benefits and risks of bariatric surgery in adults A review[J]. JAMA, 2020, 324(9): 879-887.
[5] Soong TC, Lee MH, Lee WJ, et al.Long-term efficacy of bariatric surgery for the treatment of super-obesity: comparison of SG, RYGB, and OAGB[J]. Obes Surg, 2021, 31(8): 3391-3399.
[6] Ren CJ, Patterson E, Gagner M.Early results of laparoscopic biliopancreatic diversion with duodenal switch: a case series of 40 consecutive patients[J]. Obes Surg, 2000, 10(6): 514-523.
[7] Vu AH, Chiang J, Qian Y, et al.Do all roads lead to Rome? A retrospective analysis on surgical technique in sleeve gastrectomy[J]. Surg Endosc, 2023, 37(10): 8064-8071.
[8] Kowalewski PK, Olszewski R, Waledziak MS, et al.Long-term outcomes of laparoscopic sleeve gastrectomy—a single-center, retrospective study[J]. Obes Surg, 2018, 28(1): 130-134.
[9] Vilallonga R, Hidalgo M, Garcia RD GA, et al.Operative and postoperative complications of laparoscopic sleeve gastrectomy in super and nonsuper obese patients: a center of excellence experience comparative study[J]. J Laparoendosc Adv Surg Tech A, 2020, 30(5): 501-507.
[10] Vanevik M, Lorentzen J, Borgeraas H, et al.Patient-reported outcomes, weight loss, and remission of type 2 diabetes 3 years after gastric bypass and sleeve gastrectomy (Oseberg); a single-centre, randomised controlled trial[J]. Lancet Diabetes Endocrinol, 2023, 11(8): 555-566.
[11] Lind RP, Antunes J, Ghanem M, et al.Reflux after sleeve gastrectomy: safety and effectiveness of laparoscopic ligamentum teres cardiopexy, a single-center experience[J]. Obes Surg, 2024, 34(4): 1232-1237.
[12] Almutairi BF, Aldulami AB, Yamani NM.Gastroesophageal reflux disease and hiatal hernia after laparoscopic sleeve gastrectomy: a retrospective cohort study[J]. Cureus, 2022, 14(3): e23024.
[13] Han RY, Ma J, Ma J, et al.Correlation of reproductive hormone levels and seminal plasma oxidative stress with semen quality in obese males[J]. Natl J Androl, 2018, 24(5): 419-424.
[14] Komninos D, Ramos L, Van der Heijden GW, et al. High fat diet-induced obesity prolongs critical stages of the spermatogenic cycle in a Ldlr(-/-). Leiden mouse model[J]. Sci Rep, 2022, 12(1): 430.
[15] 温玲英,温俊平. 减重手术对肥胖患者性功能和性激素水平的影响[J]. 国际内分泌代谢杂志,2017,37(2):105-107.
[16] Di Vincenzo A, Silvestrin V, Bertoli E, et al.Short-term effects of surgical weight loss after sleeve gastrectomy on sex steroids plasma levels and PSA concentration in men with severe obesity[J]. Aging Male, 2020, 23(5): 464-468.
[17] Zhu CL, Zhang Y, Zhang L, et al.Changes in sex hormones after laparoscopic sleeve gastrectomy in Chinese obese men: a 12-month follow-up[J]. Obes Surg, 2019, 29(3): 869-877.
[18] Arolfo S, Scozzari G, Di Benedetto G, et al.Surgically induced weight loss effects on sexual quality of life of obese men: a prospective evaluation[J]. Surg Endosc, 2020, 34(12): 5558-5565.
[19] El SM.Obesity, an enemy of male fertility: a mini review[J]. Oman Med J, 2018, 33(1): 3-6.
[20] Abouelgreed TA, Elatreisy A, El-sherbeiny AF, et al. Long-term effect of sleeve gastrectomy surgery on hormonal profile, semen parameters and sexual functions of obese infertile men; a prospective observational study[J]. Basic Clin Androl, 2023, 33(16): 2-7.
[21] Wei Y, Chen Q, Qian W.Effect of bariatric surgery on semen parameters: a systematic review and meta-analysis[J]. Med Sci Monit Basic Res, 2018, 24: 188-197.
[22] Javani S, Mosapour E, Hoseine S, et al.Analysis of semen parameters, and hormonal changes of FSH, LH, testosterone, and libido following bariatric surgery[J]. J Family Med Prim Care, 2023, 12(11): 2596-2601.
[23] Razzaq A, Soomro FH, Siddiq G, et al.Decrease in sperm count after bariatric surgery: case reports[J]. Cureus, 2021, 13(12): e20388.
[24] Gomez G, Berger A, Kathrins M.Secondary azoospermia after sleeve gastrectomy: a case report[J]. F S Rep, 2021, 2(2): 245-248.
[25] Calderon B, Huerta L, Galindo J, et al.Lack of improvement of sperm characteristics in obese males after obesity surgery despite the beneficial changes observed in reproductive hormones[J]. Obes Surg, 2019, 29(7): 2045-2050.
[26] Calderon B, Gomez-Martin JM, Cuadrado-Ayuso M, et al.Circulating zinc and copper levels are associated with sperm quality in obese men after metabolic surgery: a pilot study[J]. Nutrients, 2020, 12(11): 3354.
[27] Carette C, Levy R, Eustache F, et al.Changes in total sperm count after gastric bypass and sleeve gastrectomy: the BARIASPERM prospective study[J]. Surg Obes Relat Dis, 2019, 15(8): 1271-1279.
[28] Crean AJ, Senior AM.High-fat diets reduce male reproductive success in animal models: a systematic review and meta-analysis[J]. Obes Rev, 2019, 20(6): 921-933.
[29] 李佳静, 王炎秋, 卞崔冬,等.垂直束带式胃减容术改善肥胖不育雄鼠生育力模型研究[J]. 外科研究与新技术, 2018, 7(2): 89-92.
[30] Xiang J, Bian C, Wan X, et al.Sleeve gastrectomy reversed obesity-induced hypogonadism in a rat model by regulating inflammatory responses in the hypothalamus and testis[J]. Obes Surg, 2018, 28(8): 2272-2280.
[31] Litwin MS, Nied RJ, Dhanani N.Health-related quality of life in men with erectile dysfunction[J]. J Gen Intern Med, 1998, 13(3): 159-166.
[32] Rosen RC, Riley A, Wagner G, et al.The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction[J]. Urology, 1997, 49(6): 822-830.
[33] Glina F, De Freitas BJ, Nunes VM, et al.What is the impact of bariatric surgery on erectile function? A systematic review and meta-snalysis[J]. Sex Med Rev, 2017, 5(3): 393-402.
[34] Arolfo S, Scozzari G, Di Benedetto G, et al.Surgically induced weight loss effects on sexual quality of life of obese men: a prospective evaluation[J]. Surg Endosc, 2020, 34(12): 5558-5565.

袖状胃减容术对肥胖介导的男性生殖功能障碍的影响

Effect of sleeve gastrectomy on obesity-mediated male reproductive dysfunction

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 1

编辑推荐

Metrics

本文评价