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外科研究与新技术 ›› 2016, Vol. 5 ›› Issue (4): 245-247.

• 论著 • 上一篇    下一篇

早期肠内营养支持在急性胰腺炎治疗中的应用

雷滋华   

  1. 福建省建瓯市立医院外一科
  • 收稿日期:2016-08-10 修回日期:2016-08-25 出版日期:2016-12-28 发布日期:2017-02-17
  • 通讯作者: 雷滋华 E-mail:jolzh2015@sina.com

The application of early enteral nutrition support in the treatment of acute pancreatitis

  • Received:2016-08-10 Revised:2016-08-25 Online:2016-12-28 Published:2017-02-17

摘要: 目的 探讨早期肠内营养支持(EEN)在急性胰腺炎(AP)治疗中的应用。方法 回顾性分析2014年1月至2016年6月我院76例AP患者应用EEN的临床资料,记录EEN开始时机、建立途径及耐受情况,统计EN相关吸入性肺炎发生率、住院时间和预后。结果 本组轻、中、重度AP各为5、24、47例。EEN在入院后48h内开始应用25例、48~72h内51例。EEN经鼻空肠管途径46例(NJ组)、经鼻胃管途径30例(NG组)。10例出现不耐受情况,2例发生吸入性肺炎。住院时间为14~35(28.5±7.5)d。治愈71例,死亡5例。NJ组和NG组在耐受性、吸入性肺炎、住院时间和预后指标方面,差异无统计学意义(均P>0.05)。结论 中、重度急性胰腺炎患者实施EEN有助于改善预后;应综合考虑开始时间、患者胃肠道功能等因素以选择经鼻空肠管或经鼻胃管途径建立EEN。

关键词: 急性胰腺炎, 早期肠内营养支持, 鼻胃/空肠管

Abstract: Objective To explore the application of early enteral nutrition support (EEN) in the treatment of acute pancreatitis (AP). Methods The clinical data of 76 AP patients with EEN from January 2014 to June 2016 in our hospital were retrospectively analyzed. The time of starting EEN, the feeding way, and the tolerance were recorded. The incidence of EEN related inhalation pneumonia, hospitalization time and prognosis were measured. Results In this series, there were 5 cases of mild AP, 24 cases of moderate AP, 47 cases of severe AP. The time of starting EEN within 48h of admission in 25 cases, and 48~72h after admission in 51 cases. EEN feeding through nasojejunal tube in 46 cases (NJ group), and nasogastric tube in 30 cases (NG group). The intolerance of EEN occurred in 10 patients. Inhalation pneumonia occurred in 2 patients. The length of hospital stay was 14~35d with an average of 28.5±7.5d. 71 cases were cured, and 5 cases died. There was no significant difference in tolerance, inhalation pneumonia, length of stay and prognosis between NJ group and NG group (P>0.05). Conclusions EEN is helpful to improve the prognosis of patients with moderate and severe acute pancreatitis. Clinical factors such as the time of the feeding start and the gastrointestinal function should be considered for the EEN feeding through nasojejunal or nasogastric tube.

Key words: Acute pancreatitis, Early enteral nutrition support, Nasogastric/nasojejunal tube