探讨应用CO2激光治疗早期声门型喉癌临床效果

doi:10.3969/j.issn.2095-378X.2018.01.013

外科研究与新技术 ›› 2018, Vol. 7 ›› Issue (1): 45-47.doi: 10.3969/j.issn.2095-378X.2018.01.013

探讨应用CO₂激光治疗早期声门型喉癌临床效果

王海, 谷丽

山东省威海市立医院耳鼻咽喉头颈外科,威海 264200

收稿日期:2018-02-01 发布日期:2019-12-12
作者简介:王海(1985—),男,本科,医师,从事咽喉及头颈外科临床工作;电子信箱:risunxinmeng@163.com

Clinical effects of CO₂ laser on early glottic cancer

WANG Hai, GU Li

Department of Neurosurgery, Otorhinolaryngology and Stomatology, Weihai Municipal Hospital, Weihai 264200, China

Received:2018-02-01 Published:2019-12-12

摘要/Abstract

摘要： 目的探讨应用CO₂激光治疗早期声门型喉癌的临床效果。方法选择2012年5月—2017年5月在我院耳鼻咽喉头颈外科行CO₂激光治疗的40例早期声门型喉癌患者临床资料进行总结分析。其中T1a病变24例、T1b病变9例、T2病变7例;未累及前联合34例、累及前联合6例。行CO₂激光治疗后随诊时间6～72个月。结果 40例患者术后5例(12.5%)复发;其中T1a病变患者复发率为4.2%(1/24),T1b病变患者复发率为11.1%(1/9),T2病变患者复发率42.9%(3/7),经卡方检验差异具有统计学意义(χ²=7.4376,P=0.0243)。在未累及前联合的患者中,复发率为11.8%(4/34),累及前联合的患者中,复发率为16.7%(1/6),经卡方检验差异不具有统计学意义(χ²=0.1120,P=0.7378)。在所有40例患者中,存活39例(97.5%),死亡1例(2.5%)。结论 CO₂激光治疗早期声门型喉癌能较好地保全喉功能,效果确切可靠,值得推广应用。

关键词: 早期声门型喉癌, CO₂激光, 临床效果

Abstract: Objective To explore the clinical effects of CO₂ laser for early glottic cancer.Methods The clinical data of 40 cases with early glottic cancer from May 2012 to May 2017 were selected, including 24 cases of T1a lesion, 9 cases of T1b lesion, 7 cases of T2 lesion, 34 cases without involvement of glottis joint, and 6 cases with involvement of glottis joint. After CO₂ laser, the cases were followed up for 6-72 months.Results In the 40 cases, 5 cases (12.5%) recurred after surgery. The recurrence rates for T1a, T1b, and T2 lesion patients were 4.2%(1/24), 11.1%(1/9), and 42.9%(3/7), respectively (χ²=7.4376, P=0.0243). For the patients without involvement of glottis joint, the recurrence rate was 11.8% (4/34).For the patients with involvement of glottis joint, the recurrence rate was 16.7% (1/6) (χ²=0.1120, P=0.737 8). In the 40 cases, 39 (97.5%) cases survived and 1 died (2.5%).Conclusion CO₂ laser can preserve voice function of larynx with good results for early glottic cancer, thus deserving promotion.

Key words: Early glottic cancer, CO₂ laser, Clinical effects

中图分类号:

R767.91

王海, 谷丽. 探讨应用CO₂激光治疗早期声门型喉癌临床效果[J]. 外科研究与新技术, 2018, 7(1): 45-47.

WANG Hai, GU Li. Clinical effects of CO₂ laser on early glottic cancer[J]. Surgical Research and New Technique, 2018, 7(1): 45-47.

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探讨应用CO₂激光治疗早期声门型喉癌临床效果

Clinical effects of CO₂ laser on early glottic cancer

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