颅内动脉瘤介入治疗后复发风险因素探究

doi:10.3969/j.issn.2095-378X.2025.02.012

摘要/Abstract

摘要： 目的探究和分析颅内动脉瘤介入治疗后复发风险因素。方法选取2021年6月—2023年6月本院收治的40例颅内动脉瘤患者作为研究对象,患者均行介入治疗,术后随访1年,术后半年造影一次,1年后再造影一次,检查动脉瘤是否复发,根据是否复发分为复发组（11例）和未复发组（29例）,对比两组患者动脉瘤位置、动脉瘤直径、瘤颈分型、Raymond分级、治疗后是否吸烟/饮酒等资料,采用logistic多因素回归分析颅内动脉瘤介入治疗后复发风险因素,根据复发风险因素制定相应的防范策略。结果复发组和未复发组患者动脉瘤位于前/后循环的占比比较,差异无统计学意义（P>0.05）,复发组动脉瘤直径5~6 mm占比、宽颈型瘤颈占比、Raymond分级Ⅱ~Ⅲ级占比、治疗后吸烟率和饮酒率均高于未复发组,两组差异有统计学意义（均P<0.05）;多因素logistic回归分析显示,动脉瘤直径、瘤颈分型、Raymond分级、吸烟、饮酒是导致颅内动脉瘤介入治疗后复发的独立风险因素。结论引发颅内动脉瘤介入治疗后复发的风险因素有动脉瘤直径、瘤颈分型、Raymond分级、吸烟、饮酒等。建议对动脉瘤直径较大、瘤颈分型为宽颈、Raymond分级高的患者术后定期复查,并及早干预,并告诫患者术后应避免吸烟、饮酒,以降低病情复发风险。

关键词: 颅内动脉瘤, 介入治疗, 复发, 风险因素, Raymond分级

Abstract: Objective To analyze the risk factors for recurrence of intracranial aneurysms after interventional treatment. Methods Forty patients with intracranial aneurysms admitted to our hospital from June 2021 to June 2023 were selected as study subjects. All patients underwent interventional treatment and were followed up for one year after surgery. Arterial angiography was performed 6 months postoperatively and again one year later to check for recurrence. The patients were divided into a recurrence group （11 cases） and a non-recurrence group （29 cases） based on whether the aneurysm had recurred. The aneurysm location, aneurysm diameter, aneurysm neck classification, Raymond grading, smoking and alcohol consumption after treatment were compared between the two groups. Multivariate logistic regression analysis was used to identify the risk factors for recurrence of intracranial aneurysms after interventional treatment, and corresponding prevention strategies were formulated. Results There was no statistically significant difference in the location of aneurysms between the recurrence group and the non-recurrence group （P>0.05）. The recurrence group had higher incidence rates of aneurysms with a diameter of 5-6 mm, a wide neck type, and class Ⅱ-Ⅲ by Raymond grading, and smoking and alcohol consumption rates after treatment compared to the non-recurrence group （P<0.05）.The multivariate logistic regression analysis showed that aneurysm diameter, aneurysm neck classification, Raymond grading, smoking, and alcohol consumption were independent risk factors for recurrence of intracranial aneurysms after interventional treatment. Conclusion The risk factors for recurrence of intracranial aneurysms after interventional treatment include aneurysm diameter, aneurysm neck classification, Raymond grading, smoking, and alcohol consumption. It is recommended that patients with large aneurysm diameter, wide aneurysm neck classification, and high Raymond grading undergo regular postoperative follow-up and early intervention. In addition, it is recommended that patients avoid smoking and alcohol consumption after surgery to reduce the risk of disease recurrence.

Key words: Intracranial aneurysm, Interventional therapy, Recurrence, Risk factor, Raymond grading

中图分类号:

R743

王珏, 韦剑波. 颅内动脉瘤介入治疗后复发风险因素探究[J]. 外科研究与新技术（中英文）, 2025, 14(2): 153-156.

WANG Jue, WEI Jianbo. Risk factors for recurrence of intracranial aneurysms after interventional treatment[J]. Surgical Research and New Technique, 2025, 14(2): 153-156.

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