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Surgical Research and New Technique ›› 2020, Vol. 9 ›› Issue (2): 100-104.doi: 10.3969/j.issn.2095-378X.2020.02.009

• Review • Previous Articles     Next Articles

Reseach progress on development of Barrett esophagus to esophageal adenocarcinoma

YAO Liwen, XU Shuchang   

  1. Department of Gastroenterology, Tongji Hospital Affiliated to Tongji University, Shanghai 200065, China
  • Received:2020-04-22 Online:2020-06-28 Published:2020-09-16

Abstract: Barrett esophagus (BE) refers to the replacement of normal lamellar squamous epithelium in the lower esophagus by metaplasia of columnar epithelium. BE is the strongest risk for esophageal adenocarcinoma (EAC). The evolution and progression from BE to EAC has become the research focus of BE. Many key signaling factors and signaling pathways are involved. This paper reviewed the research progress on how BE evolves into EAC.

Key words: Barrett esophagus, Esophageal adenocarcinoma, Pathogenesis, Signaling pathway

CLC Number: